Kimura Koichi, Adachi Eisuke, Toyohara Ayako, Omori Sachie, Ezaki Kaoru, Ihara Ryo, Higashi Takahiro, Ohgaki Kippei, Ito Shuhei, Maehara Shin-Ichiro, Nakamura Toshihiko, Fushimi Fumiyoshi, Maehara Yoshihiko
Department of Surgery, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka 815-8588, Japan.
Department of Internal Medicine, Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka 815-8588, Japan.
World J Clin Cases. 2021 Jun 16;9(17):4453-4459. doi: 10.12998/wjcc.v9.i17.4453.
Schwannoma of the pancreas is extremely rare. We report a case of pancreatic schwannoma that was difficult to distinguish from pancreatic carcinoma before surgery.
A 66-year-old male underwent a right-lobe hepatectomy for hepatocellular carcinoma. Post-surgical computed tomography showed a 10 mm long solid mass with ischemia, with no expansion into the main pancreatic duct. Upon magnetic resonance cholangiopancreatography, the tumor had high signal intensity in diffusion weighted images, consistent with pancreatic carcinoma. Endoscopic ultrasound (EUS) was performed to obtain more information about the tumor, and showed a 14 mm solid and hypoechoic mass in the pancreatic body. Contrast enhanced EUS revealed that the tumor showed a hyperechoic mass in the early phase, and the contrasting effect continuation was very short; findings also consistent with pancreatic carcinoma. Thus, we preoperatively diagnosed his condition as a pancreatic carcinoma and performed distal pancreatectomy with splenectomy. Microscopic examination showed that the tumor was in fact a benign schwannoma. Histology showed a proliferation of spindle-shaped cell in a vague fascicular and haphazard pattern, with palisading arrangement.
Schwannoma of the pancreas is very rare, however, clinicians should consider schwannoma as the differential diagnosis for pancreatic tumors.
胰腺神经鞘瘤极为罕见。我们报告一例术前难以与胰腺癌相鉴别的胰腺神经鞘瘤病例。
一名66岁男性因肝细胞癌接受了右半肝切除术。术后计算机断层扫描显示一个10毫米长的实性肿块伴缺血,未向主胰管扩展。磁共振胰胆管造影显示,该肿瘤在扩散加权图像中呈高信号强度,与胰腺癌表现一致。为获取更多关于该肿瘤的信息,进行了内镜超声检查(EUS),结果显示胰体部有一个14毫米的实性低回声肿块。EUS造影增强显示,该肿瘤在早期呈高回声肿块,造影效果持续时间很短;这些表现也与胰腺癌相符。因此,我们术前将其病情诊断为胰腺癌,并实施了胰体尾切除术加脾切除术。显微镜检查显示,该肿瘤实际上是良性神经鞘瘤。组织学检查显示,肿瘤呈梭形细胞增生,排列成模糊的束状和杂乱无章的模式,呈栅栏状排列。
胰腺神经鞘瘤非常罕见,然而,临床医生应将神经鞘瘤作为胰腺肿瘤的鉴别诊断之一。