Abdelaziz Ben Abdessalem, Kallel Yassine, Ichraf Jbir, Beji Hazem, Chalbi Emna, Touinsi Hassen
Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia.
Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia.
Int J Surg Case Rep. 2025 Feb;127:110865. doi: 10.1016/j.ijscr.2025.110865. Epub 2025 Jan 13.
Pancreatic schwannoma (PS) is an extremely rare benign tumor also known as neurilemoma or neuroma. The majority of PS develop cystic lesions, and its preoperative diagnosis is challenging due to its tendency to mimic other lesions of the pancreas. Herein, we reported a case of body PS incidentally discovered in an 81-year-old male, which was successfully treated through enucleation.
We report the case of a 81-year-old man. Who presented with a well-defined polycystic-tumor of about 2cm at the pancreatic body, overdrawn by a computed tomography scan, incidentally discovered. The patient underwent a laparotomy, and we performed an enucleation of the tumor successfully. Histopathological examination revealed spindle-shaped cells. Immunohistochemically studies showed S100-protein expression, confirmed a body pancreatic schwannoma. The postoperative course was uneventful.
Schwannomas are rare mesenchymal-tumors, with PS accounting for only 1 % of cases. They are often difficult to diagnose as they mimic other pancreatic tumors. Imaging techniques like CT, MRI, and EUS-FNA aid in detection, but definitive diagnosis requires histological and immunohistochemical analysis. Treatment is typically enucleation for benign tumors, but larger or malignant tumors may need more extensive resections. Due to diagnostic challenges, aggressive surgeries are common. Prognosis is generally favorable, but regular follow-ups are recommended to monitor for recurrence.
Although pancreatic schwannoma is rare, it should be included in the list of differential diagnoses of pancreatic masses, both solid and cystic. Both enucleation and radical surgical resections have revealed great therapeutic efficiency with a well prognosis without recurrences.
胰腺神经鞘瘤(PS)是一种极为罕见的良性肿瘤,也被称为神经鞘瘤或神经瘤。大多数PS会发展为囊性病变,由于其倾向于模仿胰腺的其他病变,术前诊断具有挑战性。在此,我们报告一例81岁男性偶然发现的胰体PS病例,通过摘除术成功治疗。
我们报告一例81岁男性病例。该患者经计算机断层扫描偶然发现胰体有一个边界清晰的约2cm多囊性肿瘤。患者接受了剖腹手术,我们成功地进行了肿瘤摘除术。组织病理学检查显示为梭形细胞。免疫组织化学研究显示S100蛋白表达,证实为胰体神经鞘瘤。术后过程顺利。
神经鞘瘤是罕见的间叶性肿瘤,PS仅占病例的1%。它们通常难以诊断,因为它们模仿其他胰腺肿瘤。CT、MRI和EUS-FNA等成像技术有助于检测,但明确诊断需要组织学和免疫组织化学分析。良性肿瘤的治疗通常是摘除术,但较大或恶性肿瘤可能需要更广泛的切除。由于诊断具有挑战性,积极的手术很常见。预后一般良好,但建议定期随访以监测复发情况。
尽管胰腺神经鞘瘤罕见,但它应被列入胰腺实性和囊性肿块的鉴别诊断清单中。摘除术和根治性手术切除均显示出良好的治疗效果,预后良好且无复发。