Uzun Ozcan, Tamam Lut, Ozcüler Tuncay, Doruk Ali, Unal Mehmet
Department of Psychiatry, Gulhane School of Medicine, 06018 Etlik, Ankara, Turkey.
Isr J Psychiatry Relat Sci. 2009;46(3):189-94.
Suicide attempt is a universally observed human behavior related to bio-psychological, social and cultural factors. While some studies have suggested that specific demographic/cultural and clinical variables are associated with suicide attempts in schizophrenia, these associations are often inconsistent.
The aim of this study was to investigate the possible association between socio-demographic and clinical variables and suicidal behavior in a sample of patients diagnosed as having schizophrenia in Turkey.
Three hundred patients with a SCID-I diagnosis of schizophrenia were studied. The sample was subdivided into two groups based on the presence or absence of lifetime suicide attempts. The main demographic and clinical variables retrospectively collected were analyzed and compared between the two groups.
The results of present study revealed that the subjects who had and had not attempted suicide did not differ with respect to demographic variables. The suicide attempters tend to have younger age at onset of disorder, longer duration of psychosis, more hospitalizations, are more likely to have lifetime major depressive episodes, and a significantly higher rate of alcohol abuse or dependence than patients without a lifetime history of suicide attempts.
Consistent with the results of previous studies, it has been found that demographic variables may be less valuable predictors of suicidal behavior than clinical variables. These results lead to the idea that socio-cultural variations may not be a critical determinant for suicide attempt among patients with schizophrenia.
自杀未遂是一种普遍存在的人类行为,与生物心理、社会和文化因素相关。虽然一些研究表明,特定的人口统计学/文化和临床变量与精神分裂症患者的自杀未遂有关,但这些关联往往并不一致。
本研究旨在调查土耳其诊断为精神分裂症的患者样本中,社会人口统计学和临床变量与自杀行为之间可能存在的关联。
对300例经SCID-I诊断为精神分裂症的患者进行研究。根据是否有过自杀未遂史,将样本分为两组。对回顾性收集的主要人口统计学和临床变量进行分析,并在两组之间进行比较。
本研究结果显示,有自杀未遂史和无自杀未遂史的受试者在人口统计学变量方面没有差异。与无自杀未遂史的患者相比,自杀未遂者发病年龄往往更小,精神病病程更长,住院次数更多,更易有终生重度抑郁发作史,且酒精滥用或依赖率显著更高。
与先前研究结果一致,发现人口统计学变量作为自杀行为预测指标的价值可能低于临床变量。这些结果表明,社会文化差异可能不是精神分裂症患者自杀未遂的关键决定因素。