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中国精神分裂症患者自杀企图和自杀意念及其与人口统计学和临床相关性及生活质量的关系。

Suicide attempt and suicidal ideation and their associations with demographic and clinical correlates and quality of life in Chinese schizophrenia patients.

机构信息

Beijing Anding Hospital, Capital Medical University, Beijing, China.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2013 Mar;48(3):447-54. doi: 10.1007/s00127-012-0555-0. Epub 2012 Jul 31.

Abstract

OBJECTIVES

This study aimed to examine the prevalence and correlates of lifetime suicide attempts and current suicidal ideation in community-dwelling schizophrenia patients in China.

METHOD

A sample of 540 schizophrenia patients was randomly selected in Beijing, China. All subjects were interviewed using standardized assessment instruments and their basic socio-demographic and clinical data including history of suicide attempts were collected.

RESULTS

The prevalence of lifetime suicide attempts and the point prevalence of suicidal ideation were 12.0%, and 21.1%, respectively. In multiple logistic regression analyses, the presence of lifetime suicide attempt was independently associated with rural residence, having major medical conditions and better social functioning, while higher likelihood of current suicidal ideation was associated with past suicide attempt, the severity of overall psychopathology and depressive symptoms and lower psychological quality of life (QOL).

CONCLUSION

Among Chinese outpatients with schizophrenia, increased current symptoms and poorer QOL were correlated with current suicidal ideation, while demographic factors and indicators of greater social support were mostly correlated with lifetime suicide attempts. This study may help to identify important subgroups of patients with schizophrenia at particularly high risk of suicidal behavior.

摘要

目的

本研究旨在调查中国社区精神分裂症患者一生中自杀未遂和当前自杀意念的患病率及其相关因素。

方法

本研究在北京随机抽取了 540 名精神分裂症患者。所有患者均使用标准化评估工具进行访谈,并收集其基本社会人口学和临床数据,包括自杀未遂史。

结果

一生中自杀未遂的患病率和当前自杀意念的时点患病率分别为 12.0%和 21.1%。多因素 logistic 回归分析显示,一生中自杀未遂的发生与农村居住、患有重大躯体疾病和更好的社会功能有关,而当前自杀意念的发生则与既往自杀未遂、整体精神病理严重程度和抑郁症状以及较低的心理生活质量(QOL)有关。

结论

在中国精神分裂症门诊患者中,当前症状加重和 QOL 降低与当前自杀意念有关,而人口统计学因素和社会支持程度较高的指标则与一生中自杀未遂的发生有关。本研究可能有助于识别具有特别高自杀行为风险的精神分裂症患者的重要亚组。

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