Rodríguez Pedro M, Freixinet Jorge L, Plaza Maria L, Camacho Rafael
Department of Thoracic Surgery, Universitary Hospital of Gran Canaria Dr. Negrín, C/Barranco de la Ballena s/n, Las Palmas de Gran Canaria, Canary Island, Spain.
Interact Cardiovasc Thorac Surg. 2010 Mar;10(3):441-2. doi: 10.1510/icvts.2009.219386. Epub 2009 Dec 29.
Primary pleural leiomyoma is extremely rare and has only been described a few times. We present a case of a young woman with right pleuritic pain. A computed tomography confirmed the existence of a solid right pleural tumor which had compressed and displaced the lung, mediastinum and heart. Percutaneous biopsy showed a 'proliferation of smooth muscle cells without evidence of malignancy'. Surgical excision was done and the tumor was not associated to vascular, broncho-pulmonary or mediastinal structures. The definitive diagnosis was primary pleural leiomyoma. Primary pleural leiomyoma should be included in a differential diagnosis of pleural tumors and suspected in asymptomatic patients with radiologically-apparent benign tumors and the presence of smooth muscle fibers in the biopsy. Complete resection and follow-up is advised because it can grow very large and has malignant potential.
原发性胸膜平滑肌瘤极为罕见，仅被描述过几次。我们报告一例年轻女性患有右侧胸膜炎性疼痛的病例。计算机断层扫描证实存在一个实性右侧胸膜肿瘤，该肿瘤已压迫并移位肺、纵隔和心脏。经皮活检显示“平滑肌细胞增殖，无恶性证据”。进行了手术切除，肿瘤与血管、支气管肺或纵隔结构无关。最终诊断为原发性胸膜平滑肌瘤。原发性胸膜平滑肌瘤应纳入胸膜肿瘤的鉴别诊断中，对于无症状但影像学表现为良性肿瘤且活检中有平滑肌纤维的患者应予以怀疑。建议进行完整切除并随访，因为它可能长得非常大且有恶变潜能。
