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本文引用的文献

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Randomized efficacy trial of early preconception counseling for diabetic teens (READY-girls).糖尿病青少年孕前早期咨询的随机疗效试验（READY-girls）
Diabetes Care. 2008 Jul;31(7):1327-30. doi: 10.2337/dc07-1266. Epub 2008 Apr 14.
2
Trends in prevalence and outcomes of pregnancy in women with pre-existing type I and type II diabetes.患有I型和II型糖尿病的孕妇的患病率及妊娠结局趋势。
BJOG. 2008 Mar;115(4):445-52. doi: 10.1111/j.1471-0528.2007.01644.x.
3
The relationship between pre-pregnancy care and early pregnancy loss, major congenital anomaly or perinatal death in type I diabetes mellitus.I型糖尿病患者孕前护理与早期妊娠丢失、严重先天性异常或围产期死亡之间的关系。
BJOG. 2007 Jan;114(1):104-7. doi: 10.1111/j.1471-0528.2006.01145.x.
4
Is pregnancy outcome worse in type 2 than in type 1 diabetic women?2型糖尿病女性的妊娠结局是否比1型糖尿病女性更差？
Diabetes Care. 2006 Nov;29(11):2557-8. doi: 10.2337/dc06-0680.
5
Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in England, Wales, and Northern Ireland: population based study.英格兰、威尔士和北爱尔兰1型或2型糖尿病女性所生婴儿的围产期死亡率和先天性异常：基于人群的研究
BMJ. 2006 Jul 22;333(7560):177. doi: 10.1136/bmj.38856.692986.AE. Epub 2006 Jun 16.
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The pregnancies of women with Type 2 diabetes: poor outcomes but opportunities for improvement.2型糖尿病女性的妊娠：结局不佳但有改善机会。
Diabet Med. 2005 Dec;22(12):1774-7. doi: 10.1111/j.1464-5491.2005.01784.x.
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Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis.孕前保健与糖尿病女性后代先天性异常风险：一项荟萃分析。
QJM. 2001 Aug;94(8):435-44. doi: 10.1093/qjmed/94.8.435.
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Preconception care of women with diabetes: the unrevealed obstacles.糖尿病女性的孕前护理：未被揭示的障碍。
J Matern Fetal Med. 2000 Jan-Feb;9(1):10-3. doi: 10.1002/(SICI)1520-6661(200001/02)9:1<10::AID-MFM4>3.0.CO;2-Z.
9
The impact of preconception counseling on pregnancy outcomes. The experience of the Maine Diabetes in Pregnancy Program.孕前咨询对妊娠结局的影响。缅因州妊娠糖尿病项目的经验。
Diabetes Care. 1993 Feb;16(2):450-5. doi: 10.2337/diacare.16.2.450.

糖尿病女性的孕前咨询：英格兰北部的一项基于人群的研究。

Preconception counseling in women with diabetes: a population-based study in the north of England.

机构信息

Department of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, South Carolina, USA.

出版信息

Diabetes Care. 2010 Mar;33(3):586-8. doi: 10.2337/dc09-1585. Epub 2009 Dec 29.

DOI:10.2337/dc09-1585
PMID:20040652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2827513/
Abstract

OBJECTIVE To investigate the association of preconception counseling with markers of care and maternal characteristics in women with pregestational diabetes. RESEARCH DESIGN AND METHODS The study includes data from a regional multi-center survey on 588 women with pregestational diabetes who delivered a singleton pregnancy between 2001 and 2004. Logistic regression was used to obtain crude and adjusted estimates of association. RESULTS Preconception counseling was associated with better glycemic control 3 months preconception (odds ratio 1.91, 95% CI 1.10-3.04) and in the first trimester (2.05, 1.39-3.03), higher preconception folic acid intake (4.88, 3.26-7.30), and reduced risk of adverse pregnancy outcome (P = 0.027). Uptake of preconception counseling was positively associated with type 1 diabetes (1.87, 1.14-3.07) and White British ethnicity (2.56, 1.17-5.6) and negatively with deprivation score (0.78, 0.70-0.87). CONCLUSIONS Efforts are needed to improve preconception counseling rates. Uptake is associated with maternal sociodemographic characteristics.

摘要

目的

研究孕前咨询与孕前糖尿病女性的护理指标和母体特征之间的关系。

研究设计与方法

该研究纳入了 2001 年至 2004 年间进行单胎妊娠分娩的 588 例孕前糖尿病女性的区域性多中心调查数据。采用逻辑回归分析获得关联的粗估计值和调整估计值。

结果

孕前咨询与受孕前 3 个月（比值比 1.91，95%可信区间 1.10-3.04）和孕早期（2.05，1.39-3.03）血糖控制更好、孕前叶酸摄入更高（4.88，3.26-7.30）以及不良妊娠结局风险降低（P=0.027）相关。孕前咨询的接受率与 1 型糖尿病（1.87，1.14-3.07）和白种英国人种（2.56，1.17-5.6）呈正相关，与贫困评分呈负相关（0.78，0.70-0.87）。

结论

需要努力提高孕前咨询率。接受咨询与产妇社会人口学特征有关。