The Ohio State University Wexner Medical Center, Columbus, OH, USA.
The University of Colorado Barbara Davis Center, Denver, CO, USA.
J Clin Endocrinol Metab. 2021 Mar 25;106(4):952-967. doi: 10.1210/clinem/dgaa931.
This review presents an up-to-date summary on management of type 1 diabetes mellitus (T1DM) among women of reproductive age and covers the following time periods: preconception, gestation, and postpartum.
A systematic search and review of the literature for randomized controlled trials and other studies evaluating management of T1DM before pregnancy, during pregnancy, and postpartum was performed.
Preconception planning should begin early in the reproductive years for young women with T1DM. Preconception and during pregnancy, it is recommended to have near-normal glucose values to prevent adverse maternal and neonatal outcomes, including fetal demise, congenital anomaly, pre-eclampsia, macrosomia, neonatal respiratory distress, neonatal hyperbilirubinemia, and neonatal hypoglycemia.
Women with T1DM can have healthy, safe pregnancies with preconception planning, optimal glycemic control, and multidisciplinary care.
本综述对生育年龄女性 1 型糖尿病（T1DM）的管理进行了最新总结，涵盖了以下时间段：妊娠前、妊娠期和产后。
针对评估妊娠前、妊娠期间和产后 T1DM 管理的随机对照试验和其他研究进行了系统的文献检索和综述。
有 T1DM 的年轻女性应在生育期尽早开始进行妊娠前计划。建议在妊娠前和妊娠期间将血糖值控制在接近正常水平，以预防不良的母婴结局，包括胎儿死亡、先天畸形、子痫前期、巨大儿、新生儿呼吸窘迫、新生儿高胆红素血症和新生儿低血糖。
有 T1DM 的女性可以通过妊娠前计划、最佳血糖控制和多学科护理，实现健康、安全的妊娠。
