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复发性直肠癌的治疗。

Management of recurrent rectal cancer.

机构信息

Division of Colorectal Surgery, Mayo Clinic Arizona, Scottsdale, AZ, USA.

出版信息

Ann Surg Oncol. 2010 May;17(5):1343-56. doi: 10.1245/s10434-009-0861-2. Epub 2009 Dec 30.

Abstract

BACKGROUND

Here we present a concise review on the evaluation and management of locally recurrent rectal cancer, which despite marked reductions in the rate of recurrent rectal cancer remains an important problem.

METHODS

This educational review discusses the diagnosis, evaluation, and management of recurrent rectal cancer.

RESULTS

Despite improvements in both the neoadjuvant and surgical management of rectal cancer, local recurrence is still an important problem, with documented recurrence rates of 4% to 8%. The local management of recurrence requires a team of specialist. Accurate detection and diagnosis followed by chemoradiotherapy and surgical resection may result in 5-year survival rates of up to 35%.

CONCLUSIONS

We discuss the diagnosis, evaluation, and management of locally recurrent rectal cancer. Locally recurrent rectal cancer can be successfully managed with multimodal therapy leading to successful palliation and often cure.

摘要

背景

我们在此简要介绍了局部复发性直肠癌的评估和管理,尽管直肠癌的复发率显著降低,但这仍然是一个重要问题。

方法

本教育性综述讨论了复发性直肠癌的诊断、评估和管理。

结果

尽管直肠癌的新辅助治疗和手术治疗都有所改善,但局部复发仍然是一个重要问题,已有文献报道的复发率为 4%至 8%。复发性疾病的局部管理需要一组专家。准确的检测和诊断,然后进行放化疗和手术切除,可能会导致 5 年生存率高达 35%。

结论

我们讨论了局部复发性直肠癌的诊断、评估和管理。局部复发性直肠癌可以通过多模式治疗成功管理,从而实现成功的姑息治疗,并且常常可以治愈。

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