Mycoses. 2011 Jul;54(4):e233-6. doi: 10.1111/j.1439-0507.2009.01835.x. Epub 2009 Dec 23.
Invasive aspergillosis (IA) is a major cause of death among patients with chronic granulomatous disease (CGD). Few cases of cardiac aspergillosis have been published on CGD patients. Diagnosis of IA in CGD patients can be hampered by lack of characteristic symptoms and clinical signs and the serum galactomannan assay is often negative. We report the first CGD patient with IA presenting as pericarditis where combined antifungal therapy resulted in a successful outcome.
侵袭性曲霉病（IA）是慢性肉芽肿病（CGD）患者死亡的主要原因。关于 CGD 患者的心脏曲霉病病例很少见。CGD 患者的 IA 诊断可能因缺乏特征性症状和临床体征以及血清半乳甘露聚糖检测常呈阴性而受到阻碍。我们报告了首例以心包炎为表现的 CGD 患者合并 IA，联合抗真菌治疗取得了成功的结果。
