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2006 年纽约市监狱新入狱者中未确诊的 HIV 感染:一项盲血清学调查的结果。

Undiagnosed HIV infection among New York City jail entrants, 2006: results of a blinded serosurvey.

机构信息

New York City Department of Health and Mental Hygiene, 346 Broadway, Room 707, New York, NY 10013, USA.

出版信息

J Acquir Immune Defic Syndr. 2010 May 1;54(1):93-101. doi: 10.1097/QAI.0b013e3181c98fa8.

Abstract

OBJECTIVE

Since 2004, when all New York City jail entrants began being offered rapid testing at medical intake, HIV testing has increased 4-fold. To guide further service improvement, we determined HIV prevalence among jail entrants, including proportion undiagnosed.

METHODS

Remnant serum from routine syphilis screening was salvaged for blinded HIV testing in 2006. Using HIV surveillance data and electronic clinical data, we ascertained previously diagnosed HIV infections before permanently removing identifiers. We defined "undiagnosed" as HIV-infected entrants who were unreported to surveillance and denied HIV infection.

RESULTS

Among the 6411 jail entrants tested (68.9% of admissions), HIV prevalence was 5.2% overall (males 4.7%; females: 9.8%). Adjusting for those not in the serosurvey, estimated seroprevalence is 8.7% overall (6.5% males, 14% females). Overall, 28.1% of HIV infections identified in the serosurvey were undiagnosed at jail entry; only 11.5% of these were diagnosed during routine jail testing. Few (11.1%) of the undiagnosed inmates reported injection drug use or being men who have sex with men.

CONCLUSIONS

About 5%-9% of New York City jail entrants are HIV infected. Of the infected, 28% are undiagnosed; most of whom denied recognized HIV risk factors. To increase inmate's acceptance of routine testing, we are working to eliminate the required separate written consent for HIV testing to allow implementation of the Centers for Disease Control and Prevention-recommended opt out testing model.

摘要

目的

自 2004 年以来,当所有进入纽约市监狱的人在医疗入院时都开始接受快速检测以来,艾滋病毒检测增加了 4 倍。为了进一步指导服务的改进,我们确定了监狱新入监者中的艾滋病毒流行率,包括未被诊断的比例。

方法

2006 年,从常规梅毒筛查的剩余血清中回收用于盲法艾滋病毒检测。利用艾滋病毒监测数据和电子临床数据,我们确定了在永久删除标识符之前已确诊的艾滋病毒感染。我们将“未被诊断”定义为未向监测报告且否认艾滋病毒感染的艾滋病毒感染新入监者。

结果

在接受检测的 6411 名监狱新入监者(占入院人数的 68.9%)中,艾滋病毒流行率总体为 5.2%(男性为 4.7%;女性为 9.8%)。调整未参加血清监测的人员后,估计总体血清阳性率为 8.7%(男性为 6.5%,女性为 14%)。总体而言,在血清监测中发现的艾滋病毒感染中有 28.1%在监狱入监时未被诊断;其中只有 11.5%是在常规监狱检测中被诊断出来的。在未被诊断的囚犯中,很少有人(11.1%)报告使用注射毒品或与男性发生性关系。

结论

约 5%-9%的纽约市监狱新入监者感染了艾滋病毒。在感染人群中,有 28%未被诊断;其中大多数否认存在艾滋病毒感染的已知风险因素。为了提高囚犯对常规检测的接受度,我们正在努力消除对艾滋病毒检测的单独书面同意要求,以允许实施疾病预防控制中心建议的选择退出检测模式。

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