Yale University School of Medicine, Section of Infectious Diseases, AIDS Program, New Haven, Connecticut, United States of America.
PLoS One. 2009 Nov 25;4(11):e7648. doi: 10.1371/journal.pone.0007648.
Ten million Americans enter jails annually. The objective was to evaluate new CDC guidelines for routine opt-out HIV testing and examine the optimal time to implement routine opt-out HIV testing among newly incarcerated jail detainees.
This prospective, controlled trial of routine opt-out HIV testing was conducted among 323 newly incarcerated female inmates in Connecticut's only women's jail. 323 sequential entrants to the women's jail over a five week period in August and September 2007 were assigned to be offered routine opt-out HIV testing at one of three points after incarceration: immediate (same day, n = 108), early (next day, n = 108), or delayed (7 days, n = 107). The primary outcome was the proportion of women in each group consenting to testing.
Routine opt-out HIV testing was significantly highest (73%) among the early testing group compared to 55% for immediate and 50% for 7 days post-entry groups. Other factors significantly (p = 0.01) associated with being HIV tested were younger age and low likelihood of early release from jail based on bond value or type of charge for which women were arrested.
In this correctional facility, routine opt-out HIV testing in a jail setting was feasible, with highest rates of testing if performed the day after incarceration. Lower testing rates were seen with immediate testing, where there is a high prevalence of inability or unwillingness to test, and with delayed testing, where attrition from jail increases with each passing day.
ClinicalTrials.gov NCT00624247.
每年有 1000 万美国人入狱。本研究旨在评估美国疾病控制与预防中心(CDC)关于常规选择性 HIV 检测的新指南,并探讨在新入狱的囚犯中实施常规选择性 HIV 检测的最佳时间。
这是一项在康涅狄格州唯一的女子监狱中进行的常规选择性 HIV 检测的前瞻性、对照试验,共纳入 323 名新入狱的女性囚犯。2007 年 8 月至 9 月的五周内,连续有 323 名新入狱的女性囚犯进入该女子监狱,她们被分为三组,分别在入狱后不同时间点接受常规选择性 HIV 检测:立即(同日,n = 108)、早期(次日,n = 108)或延迟(7 天,n = 107)。主要结局是每组中同意接受检测的女性比例。
早期检测组的常规选择性 HIV 检测率最高(73%),明显高于立即检测组(55%)和 7 天后检测组(50%)。其他与接受 HIV 检测显著相关的因素是年龄较小和基于保释金价值或被捕罪名,女性提前出狱的可能性较低。
在这个惩教设施中,常规选择性 HIV 检测在监狱环境中是可行的,如果在入狱后第一天进行,检测率最高。立即检测的检测率较低,原因是无法或不愿意检测的比例较高;延迟检测的检测率较低,原因是随着时间的推移,监狱中的流失率会增加。
ClinicalTrials.gov NCT00624247。