School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne, Australia.
J Head Trauma Rehabil. 2010 Sep-Oct;25(5):320-9. doi: 10.1097/HTR.0b013e3181c8f8e7.
To investigate predictors of posttraumatic brain injury psychiatric disorders.
Retrospective, cross-sectional design with stratified random sampling of groups of patients on average 1 to 5 years postinjury. DSM-based diagnostic interviews of both traumatic brain injury (TBI) participant and informant.
One hundred community-based participants, aged 19-74 years, with traumatic brain injury sustained 0.05-5.5 years previously.
Community-based patients previously treated at a rehabilitation hospital.
The Structured Clinical Interview for DSM-IV diagnosis.
A psychiatric history was a high-risk factor for having the same disorder postinjury. However, the majority of cases of depression and anxiety were novel, suggesting that significant factors other than pre-TBI psychiatric status contribute to post-TBI psychiatric outcome. Female gender, lower education, and pain were also associated with postinjury depression and unemployment and older age with anxiety.
Findings suggest that long-term screening and support are important for individuals with TBI, regardless of preinjury psychiatric status.
探讨创伤性脑损伤后精神障碍的预测因素。
采用回顾性、横断面设计，对平均伤后 1 至 5 年的患者进行分组的分层随机抽样。对创伤性脑损伤（TBI）患者和知情人进行基于 DSM 的诊断访谈。
100 名年龄在 19-74 岁之间的社区患者，曾在康复医院接受治疗，创伤性脑损伤发生在 0.05-5.5 年前。
社区患者以前曾在康复医院接受治疗。
DSM-IV 诊断的结构临床访谈。
有精神病史是受伤后出现相同障碍的高危因素。然而，大多数抑郁和焦虑症是新出现的，这表明除了创伤前的精神状态外，还有其他重要因素会影响创伤后的精神预后。女性、较低的教育程度和疼痛也与受伤后的抑郁和失业有关，而年龄较大则与焦虑有关。
研究结果表明，无论受伤前的精神状态如何，对 TBI 患者进行长期筛查和支持都很重要。
