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全国共病调查复制研究中美国老年人情绪、焦虑和物质使用障碍的患病率。

Prevalence of mood, anxiety, and substance-abuse disorders for older Americans in the national comorbidity survey-replication.

作者信息

Gum Amber M, King-Kallimanis Bellinda, Kohn Robert

机构信息

Department of Aging and Mental Health Disparities, Louis de la Parte Florida Mental Health Institute, University of South Florida, Tampa, FL, USA.

出版信息

Am J Geriatr Psychiatry. 2009 Sep;17(9):769-81. doi: 10.1097/JGP.0b013e3181ad4f5a.

Abstract

OBJECTIVES

Current information on the prevalence of psychiatric disorders among older adults in the United States is lacking. Prevalence of anxiety, mood, and substance disorders was examined by age (18-44, 45-64, 65-74, and 75 years and older) and sex. Covariates of disorders for older adults (65 years and older) were explored.

DESIGN

Cross-sectional epidemiologic study, using data from the National Comorbidity Survey-Replication.

SETTING

Community-based epidemiologic survey.

PARTICIPANTS

Representative national sample of community-dwelling adults in the United States.

MEASUREMENTS

The World Health Organization Composite International Diagnostic Interview was used to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders.

RESULTS

Prevalence of 12-month and lifetime mood, anxiety, and substance-use disorders was lower for older adults (65 years and older) than younger age groups: 2.6% for mood disorder, 7.0% for anxiety disorder, 0 for any substance-use disorder, and 8.5% for any of these disorders (for any disorder, 18-44 years = 27.6%, 45-64 years = 22.4%). Among older adults, presence of a 12-month anxiety disorder was associated with female sex, lower education, being unmarried, and three or more chronic conditions. Presence of a 12-month mood disorder was associated with disability. Similar patterns were noted for lifetime disorders (any disorder: 18-44 years = 46.4%, 45-64 years = 43.7%, and 65 years and older = 20.9%).

CONCLUSIONS

This study documents the continued pattern of lower rates of formal diagnoses for elders. These rates likely underestimate the burden of late-life psychiatric disorders, given the potential for underdiagnosis, clinical significance of subthreshold symptoms, and lack of representation from high-risk older adults (e.g., medically ill, long-term care residents).

摘要

目的

美国缺乏关于老年人精神障碍患病率的当前信息。按年龄(18 - 44岁、45 - 64岁、65 - 74岁以及75岁及以上)和性别对焦虑、情绪及物质使用障碍的患病率进行了研究。探讨了老年人(65岁及以上)精神障碍的协变量。

设计

横断面流行病学研究,使用来自全国共病调查复制版的数据。

背景

基于社区的流行病学调查。

参与者

美国社区居住成年人的代表性全国样本。

测量

采用世界卫生组织综合国际诊断访谈来评估《精神疾病诊断与统计手册》第四版中的精神障碍。

结果

老年人(65岁及以上)12个月及终生的情绪、焦虑和物质使用障碍患病率低于年轻年龄组:情绪障碍为2.6%,焦虑障碍为7.0%,任何物质使用障碍为0,这些障碍中的任何一种为8.5%(对于任何障碍,18 - 44岁 = 27.6%,45 - 64岁 = 22.4%)。在老年人中,12个月焦虑障碍的存在与女性、低教育程度、未婚以及三种或更多慢性疾病相关。12个月情绪障碍的存在与残疾相关。终生障碍也有类似模式(任何障碍:18 - 44岁 = 46.4%,45 - 64岁 = 43.7%,65岁及以上 = 20.9%)。

结论

本研究记录了老年人正式诊断率持续较低的模式。鉴于存在漏诊的可能性、阈下症状的临床意义以及高危老年人(如患有内科疾病者、长期护理机构居民)未被纳入,这些比率可能低估了晚年精神障碍的负担。

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