Nat Rev Drug Discov. 2010 Jan;9(1):17-8. doi: 10.1038/nrd3073.
In October 2009, pazopanib (Votrient; GlaxoSmithKline)--a multikinase inhibitor with targets that include vascular endothelial growth factor receptors--was approved by the US FDA for the treatment of advanced renal cell carcinoma.
2009 年 10 月,帕唑帕尼(培唑帕尼;葛兰素史克)——一种具有包括血管内皮生长因子受体在内的多种激酶靶点的抑制剂——被美国食品药品监督管理局批准用于治疗晚期肾细胞癌。