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猫科动物细菌性尿路感染:一个不断演变的临床问题的最新进展。

Feline bacterial urinary tract infections: An update on an evolving clinical problem.

机构信息

Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, 625 Harrison St., West Lafayette, IN 47907, USA.

出版信息

Vet J. 2011 Jan;187(1):18-22. doi: 10.1016/j.tvjl.2009.12.006. Epub 2009 Dec 30.

DOI:10.1016/j.tvjl.2009.12.006
PMID:20044282
Abstract

Although feline urine is increasingly submitted for bacterial culture and susceptibility testing as part of a more general diagnostic work-up for a range of presentations in veterinary practice, bacterial urinary tract infections (UTIs) are relatively uncommon due to a variety of physical and immunological barriers to infection. Culture positive urine is most often obtained from older female cats and the clinical history may include hematuria, dysuria and pollakiuria, or the infection may be occult. Urinalysis usually reveals hematuria and pyuria, and Escherichia coli and Gram-positive cocci are cultured most frequently. Most feline UTIs can be successfully treated using oral amoxicillin or amoxicillin/clavulanic acid administered for at least 14days, but the prevalence of antimicrobial resistance amongst infecting bacterial species is a growing concern. There is currently no conclusive information on the safety and efficacy of alternative therapeutic agents for the treatment of feline UTIs.

摘要

尽管猫尿越来越多地被提交进行细菌培养和药敏试验,作为兽医实践中一系列表现的更广泛诊断检查的一部分,但由于感染的各种生理和免疫屏障,细菌性尿路感染(UTI)相对较少见。阳性培养的尿液最常从老年雌性猫中获得,临床病史可能包括血尿、排尿困难和多尿,或者感染可能是隐匿性的。尿液分析通常显示血尿和脓尿,最常培养出大肠杆菌和革兰阳性球菌。大多数猫的 UTI 可以成功地用口服阿莫西林或阿莫西林/克拉维酸治疗,至少 14 天,但感染细菌物种的抗生素耐药性日益受到关注。目前,对于替代治疗药物治疗猫 UTI 的安全性和疗效尚无明确信息。

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