The University of Queensland, Centre for Magnetic Resonance, Brisbane, Australia.
Neuroimage. 2010 Apr 1;50(2):796-801. doi: 10.1016/j.neuroimage.2009.12.067. Epub 2010 Jan 4.
It is well established that the time to name target objects can be influenced by the presence of categorically related versus unrelated distractor items. A variety of paradigms have been developed to determine the level at which this semantic interference effect occurs in the speech production system. In this study, we investigated one of these tasks, the postcue naming paradigm, for the first time with fMRI. Previous behavioural studies using this paradigm have produced conflicting interpretations of the processing level at which the semantic interference effect takes place, ranging from pre- to post-lexical. Here we used fMRI with a sparse, event-related design to adjudicate between these competing explanations. We replicated the behavioural postcue naming effect for categorically related target/distractor pairs, and observed a corresponding increase in neuronal activation in the right lingual and fusiform gyri-regions previously associated with visual object processing and colour-form integration. We interpret these findings as being consistent with an account that places the semantic interference effect in the postcue paradigm at a processing level involving integration of object attributes in short-term memory.
众所周知，命名目标对象的时间会受到类别相关和不相关干扰项的影响。已经开发了多种范式来确定在言语产生系统中发生这种语义干扰效应的水平。在这项研究中，我们首次使用 fMRI 研究了其中一种任务，即后提示命名范式。以前使用该范式的行为研究对语义干扰效应发生的处理水平产生了相互矛盾的解释，范围从词汇前到词汇后。在这里，我们使用稀疏的、基于事件的设计的 fMRI 来裁决这些相互竞争的解释。我们复制了行为后提示命名效应，对于类别相关的目标/干扰对，并且在右侧舌回和梭状回中观察到相应的神经元激活增加，这些区域以前与视觉对象处理和颜色-形式整合有关。我们将这些发现解释为与一种解释一致，该解释将后提示范式中的语义干扰效应置于涉及短期记忆中对象属性整合的处理水平。
