CHU Clermont Ferrand, Department of Obstetrics and Gynecology, La Polyclinique, Clermont-Ferrand, France.
Fertil Steril. 2010 Apr;93(6):2074.e1-6. doi: 10.1016/j.fertnstert.2009.11.004. Epub 2010 Jan 4.
To report a case of endometriosis degenerated into clear cell carcinoma with positron-emission tomography (PET) scan staging.
Case report.
University hospital.
PATIENT(S): A 43-year-old woman diagnosed with endometriosis degenerated into clear cell carcinoma with nodal metastasis at the initial diagnosis and exclusive nodal recurrence 6 months after surgery.
INTERVENTION(S): Resection of the mass with partial resection of the pubic symphysis and bilateral external iliac lymphadenectomy. Forty-five days later, hysterectomy with bilateral adnexectomy and then adjuvant chemotherapy and abdominal-pelvic radiotherapy.
MAIN OUTCOME MEASURE(S): The PET scan showed positive lymph nodes in the cervical, supraclavicular, bilateral axillary, bilateral inguinal, and lumbar-aortic regions.
RESULT(S): The patient experienced a tumor recurrence after 6 months. After surgical management, she was scheduled to receive six cycles of rescue chemotherapy. She died 22 months after the initial diagnosis.
CONCLUSION(S): The use of PET scan could allow better staging at the initial diagnosis and improve follow-up in such patients. The treatment of this entity is based on radical surgery associated with adjuvant chemotherapy and radiotherapy, but the results are not satisfactory.
报告 1 例经正电子发射断层扫描(PET)分期的子宫内膜异位症恶变透明细胞癌病例。
病例报告。
大学医院。
一名 43 岁女性,初始诊断为子宫内膜异位症恶变透明细胞癌伴淋巴结转移,手术 6 个月后仅出现淋巴结复发。
行肿块切除术,包括耻骨联合部分切除术和双侧髂外淋巴结清扫术。45 天后行子宫切除术、双侧附件切除术,然后行辅助化疗和腹部-盆腔放疗。
PET 扫描显示颈部、锁骨上、双侧腋窝、双侧腹股沟和腰主动脉区域的淋巴结呈阳性。
患者在 6 个月后出现肿瘤复发。经手术治疗后,她计划接受 6 个周期的挽救性化疗。初始诊断后 22 个月死亡。
在初始诊断时使用 PET 扫描可进行更好的分期,并改善此类患者的随访。该实体的治疗基于根治性手术联合辅助化疗和放疗,但结果并不理想。