Sanli Hatice, Akay Bengü Nisa, Sen Bilge Bulbul, Kocak Aslihan Yonca, Emral Rifat, Bostanci Seher
Department of Dermatology; Ankara University School of Medicine; Ankara, Turkey.
Dermatoendocrinol. 2009 Jan;1(1):34-6. doi: 10.4161/derm.1.1.7170.
Acquired ichthyosis is an uncommon disease which is characterized by symmetric scaling of the skin. Acquired ichthyosis has been described in association with a variety of underlying causes, including malignancies, drugs, infections, endocrine, metabolic and autoimmune diseases. Acquired ichthyosis associated with diabetes mellitus has been reported only in one case. We report the case of a new-onset diabetes mellitus with a one-month history of generalized acquired ichthyosis and palmoplantar keratoderma corroborated with skin biopsy, which completely disappeared after regulation of blood glucose levels with insulin therapy.
获得性鱼鳞病是一种罕见疾病,其特征为皮肤出现对称性鳞屑。已报道获得性鱼鳞病与多种潜在病因相关,包括恶性肿瘤、药物、感染、内分泌、代谢及自身免疫性疾病。仅1例报告了与糖尿病相关的获得性鱼鳞病。我们报告1例新发糖尿病患者,有1个月全身性获得性鱼鳞病及掌跖角化病病史,经皮肤活检证实,在胰岛素治疗使血糖水平得到控制后,这些症状完全消失。