Kim Ji Hyun, Bae Hyoung Won, Lee Kwang Kil, Kim Tae Im, Kim Eung Kweon
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, #134 Sinchon-dong, Seodaemun-gu, Seoul, Korea.
Korean J Ophthalmol. 2009 Dec;23(4):306-8. doi: 10.3341/kjo.2009.23.4.306. Epub 2009 Dec 4.
Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Clinically, a diagnosis of conjunctival papilloma was made, and a mass excision was performed. The histopathological analysis evidenced a conjunctival-covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. With the above findings, a diagnosis of conjunctival seborrheic keratosis was established. The occurrence of seborrheic keratosis on the conjunctiva is rare. In this case, seborrheic keratosis was confirmed by pathologic report despite its similar appearance with papilloma. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival lesions.
脂溢性角化病是一种主要发生于眼睑和面部皮肤的良性上皮性肿瘤。我们描述一例经组织病理学证实的结膜脂溢性角化病病例。一名72岁男性患者，其右眼鼻侧出现复发性结膜肿物。临床上诊断为结膜乳头状瘤，并进行了肿物切除术。组织病理学分析显示，结膜覆盖上皮有乳头状改变和不规则棘皮症，以基底样细胞增生为代价。此外，病变呈现多个含有角蛋白的假角囊肿。根据上述发现，确诊为结膜脂溢性角化病。结膜发生脂溢性角化病较为罕见。在该病例中，尽管脂溢性角化病外观与乳头状瘤相似，但经病理报告得以确诊。在结膜病变的鉴别诊断中应考虑脂溢性角化病。
