Priya Mohanty J, Nath L K, Bhuyan Nihar, Mariappan G
Himalayan Pharmacy Institute, Majhitar, Rangpo, East Sikkim-737 132, India.
Indian J Pharm Sci. 2008 May-Jun;70(3):362-4. doi: 10.4103/0250-474X.43002.
The plant Kaempferia rotunda Linn. has been explored for its anti oxidant potential in the present study. The antioxidant property was assessed by lipid peroxidation markers such as malonaldehyde (MDA) and 4-hydroxyl-2-nonenal (4-HNE). The lipid peroxidation byproducts are highly toxic and responsible for various diseases like myocardial infarction, diabetes mellitus, hepatic injury, atherosclerosis, rheumatoid arthritis and cancer. The chemical constituents of the plant were critically and qualitatively analyzed to confirm the presence of flavonoids and phenolic derivatives. Hence our objective has been designed to evaluate the antioxidant effect of Kaempferia rotunda linn. and its contribution to control the lipid peroxidation.
在本研究中,对植物圆叶山柰(Kaempferia rotunda Linn.)的抗氧化潜力进行了探索。通过脂质过氧化标志物如丙二醛(MDA)和4-羟基-2-壬烯醛(4-HNE)来评估其抗氧化特性。脂质过氧化副产物具有高毒性,是导致心肌梗死、糖尿病、肝损伤、动脉粥样硬化、类风湿性关节炎和癌症等各种疾病的原因。对该植物的化学成分进行了严格的定性分析,以确认黄酮类化合物和酚类衍生物的存在。因此,我们的目标是评估圆叶山柰的抗氧化作用及其对控制脂质过氧化的贡献。