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拟南芥 MAPK 枢纽中的汇聚和特异性。

Convergence and specificity in the Arabidopsis MAPK nexus.

机构信息

Department of Cell and Organism Biology, Lund University, SE-223 62 Lund, Sweden.

出版信息

Trends Plant Sci. 2010 Feb;15(2):106-13. doi: 10.1016/j.tplants.2009.12.001. Epub 2010 Jan 4.

Abstract

Although mitogen-activated protein kinase (MAPK) signal transduction cascades are known regulators of various aspects of plant biology, our knowledge of these systems has been largely restricted to a small subset of the MAPKs. However, global analyses are now revealing that many more of these kinases are probably engaged in modulating developmental and fitness adaptation processes in the plant kingdom. In this review, we show how these new findings are beginning to define the overall architecture of plant MAPK signaling, with a particular focus on the interplay between the terminal MPKs and their activators, inactivators and cellular targets.

摘要

虽然丝裂原活化蛋白激酶(MAPK)信号转导级联是各种植物生物学方面的已知调节剂,但我们对这些系统的了解在很大程度上仅限于一小部分 MAPKs。然而,全球分析现在表明,这些激酶中的许多可能参与调节植物王国的发育和适应性过程。在这篇综述中,我们展示了这些新发现如何开始定义植物 MAPK 信号的总体结构,特别关注终端 MPKs 与其激活剂、失活剂和细胞靶标的相互作用。

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