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慢性交通相关 PM 暴露与 RHINE 塔尔图队列中自我报告的呼吸和心血管健康。

Chronic traffic-induced PM exposure and self-reported respiratory and cardiovascular health in the RHINE Tartu Cohort.

机构信息

Department of Public Health, University of Tartu, Estonia.

出版信息

Int J Environ Res Public Health. 2009 Nov;6(11):2740-51. doi: 10.3390/ijerph6112740. Epub 2009 Oct 30.

Abstract

The relationship between exposure to traffic induced particles, respiratory health and cardiac diseases was studied in the RHINE Tartu cohort. A postal questionnaire with commonly used questions regarding respiratory symptoms, cardiac disease, lifestyle issues such as smoking habits, indoor environment, occupation, early life exposure and sleep disorders was sent to 2,460 adults. The annual concentrations of local traffic induced particles were modelled with an atmospheric dispersion model with traffic flow data, and obtained PM(exhaust) concentrations in 40 x 40 m grids were linked with home addresses with GIS. The relationship between the level of exhaust particles outside home and self-reported health problems were analyzed using a multiple logistic regression model. We found a significant relation between fine exhaust particles and cardiac disease, OR = 1.64 (95% CI 1.12-2.43) for increase in PM(exhaust) corresponding to the fifth to the 95th percentile range. The associations also were positive but non-significant for hypertension OR = 1.42 (95% CI 0.94-2.13), shortness of breath OR = 1.27 (95% CI 0.84-1.94) and other respiratory symptoms.

摘要

交通诱导颗粒物暴露、呼吸健康与心脏疾病之间的关系在 RHINE 塔尔图队列中得到了研究。我们向 2460 名成年人邮寄了一份调查问卷,其中包含有关呼吸症状、心脏疾病、生活方式(如吸烟习惯)、室内环境、职业、早期生活暴露和睡眠障碍等常见问题。利用大气扩散模型和交通流量数据对当地交通诱导颗粒物的年度浓度进行建模,并将获得的 40x40 米网格内的 PM(尾气)浓度与 GIS 中的家庭住址相关联。我们使用多变量逻辑回归模型分析了家庭以外尾气颗粒水平与自我报告健康问题之间的关系。我们发现细颗粒尾气与心脏疾病之间存在显著关系,PM(尾气)浓度对应于第 5 至 95 个百分位数范围的增加,OR = 1.64(95%置信区间 1.12-2.43)。高血压的相关性也呈阳性但无统计学意义,OR = 1.42(95%置信区间 0.94-2.13),呼吸急促 OR = 1.27(95%置信区间 0.84-1.94)和其他呼吸症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe24/2800058/f8c22c73b5d6/ijerph-06-02740f1.jpg

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