Lievaart A, Voerman H J
Medical Intensive Care Unit, Free University Hospital, Amsterdam, The Netherlands.
Heart Lung. 1991 Mar;20(2):152-8.
Intermittent hemodialysis in critically ill patients is often accompanied by circulatory instability and hypotension. Slow continuous ultrafiltration and continuous arteriovenous hemofiltration were developed to manage fluid balance and electrolyte abnormalities without circulatory side effects. To improve urea clearance a dialysate was added to the extracorporeal circuit. This technique is called continuous arteriovenous hemodialysis (CAVHD) or, when large amounts of ultrafiltrate are removed together with the use of a substitution fluid, continuous arteriovenous hemodiafiltration. We have used CAVHD since 1987 in a medical intensive care unit. Intermittent hemodialysis is no longer used because urea clearance is adequate even in patients with severe catabolism. An initial dialysate rate of 1600 ml/hr is used. Electrolyte and glucose levels should be monitored frequently. Bleeding complications (10%) and catheter-related infection (5%) occur infrequently. An overview of the CAVHD technique is presented as well as guidelines regarding technical and nursing observations for patients receiving CAVHD treatment.
重症患者进行间歇性血液透析时常常伴有循环不稳定和低血压。为了在不产生循环副作用的情况下管理液体平衡和电解质异常,人们开发了缓慢持续超滤和持续动静脉血液滤过技术。为提高尿素清除率,在体外循环中加入了透析液。这项技术被称为持续动静脉血液透析(CAVHD),或者当与置换液一起大量清除超滤液时,称为持续动静脉血液透析滤过。自1987年以来,我们在医疗重症监护病房使用CAVHD。由于即使是严重分解代谢的患者,尿素清除率也足够,所以不再使用间歇性血液透析。初始透析液流速为1600毫升/小时。应频繁监测电解质和葡萄糖水平。出血并发症(10%)和导管相关感染(5%)很少发生。本文介绍了CAVHD技术的概述以及接受CAVHD治疗患者的技术和护理观察指南。