Department of Hematology, Shanghai Sixth People's Hospital, Shanghai JiaoTong University, 600 Yi Shan Road, 200233 Shanghai, People's Republic of China.
Med Oncol. 2011 Mar;28(1):202-6. doi: 10.1007/s12032-009-9405-7. Epub 2010 Jan 5.
The purpose of this study was to investigate the clinical signs and therapy of primary lymphoma of bone (PLB). One primary lymphoma of bone is described, and review of the pertinent literature is introduced. The patient achieved complete remission with no evidence of local recurrence. PLB are uncommon malignancies. Patients with PLB commonly present with local bone pain, soft tissue swelling and a mass or a pathological fracture. Most cases of PLB are classified as diffuse large B-cell lymphomas in the WHO classification of hematological malignancies. Comprehensive immunohistochemical studies are required to establish an accurate histological diagnosis of PLB. Early diagnosis and active treatment can improve the prognosis.
本研究旨在探讨原发性骨淋巴瘤（PLB）的临床特征和治疗方法。描述了 1 例原发性骨淋巴瘤，并对相关文献进行了回顾。患者完全缓解，无局部复发证据。PLB 是一种罕见的恶性肿瘤。PLB 患者常表现为局部骨痛、软组织肿胀、肿块或病理性骨折。大多数 PLB 病例在 WHO 血液恶性肿瘤分类中被归类为弥漫性大 B 细胞淋巴瘤。需要进行全面的免疫组织化学研究才能对 PLB 做出准确的组织学诊断。早期诊断和积极治疗可以改善预后。
