Manchester Heart Centre, Manchester Royal Infirmary, Biomedical Research Centre, Manchester, United Kingdom.
Catheter Cardiovasc Interv. 2010 Mar 1;75(4):596-602. doi: 10.1002/ccd.22246.
The aim of this study is to investigate the feasibility of using a 6.5 Fr sheathless guide catheter as a default system in transradial (TRA) percutaneous coronary intervention (PCI).
TRA PCI has been shown to reduce mortality rates through a reduction in access site related bleeding complications compared with procedures performed though a femoral approach. Complications associated with the TRA route increase with the size of sheath used. These complications may be reduced by the use of a sheathless guide catheter system (Asahi Intecc, Japan) that is 1-2 Fr sizes smaller in diameter than the corresponding introducer sheath.
We performed PCI in 100 consecutive cases using 6.5 Fr sheathless guides to determine the procedural success, rates of symptomatic radial spasm and radial occlusion.
Procedural success using the 6.5 Fr sheathless guide catheter system was 100% with no cases requiring conversion to a conventional guide and catheter system. There were no procedural complications recorded associated with the use of the catheter. Adjunctive devices used in this cohort included IVUS, stent delivery catheters, distal protection devices, and simple thrombectomy catheters. The rate of radial spasm was 5% and the rate of radial occlusion at 2 months was 2%.
Use of the 6.5 Fr sheathless guide catheter system, which has an outer diameter <5 Fr sheath, as the default system in routine PCI is feasible with a high rate of procedural success via the radial artery.
本研究旨在探讨使用 6.5Fr 无鞘导引导管作为经桡动脉(TRA)经皮冠状动脉介入治疗(PCI)的默认系统的可行性。
TRA PCI 已被证明可降低死亡率,其通过减少与股动脉入路相关的出血并发症来实现。TRA 入路相关的并发症随着鞘管尺寸的增加而增加。这些并发症可以通过使用比相应的导入鞘管小 1-2Fr 直径的无鞘导引导管系统(日本朝日英特克)来减少。
我们对 100 例连续病例进行了 PCI,使用 6.5Fr 无鞘导引导管来确定手术成功率、症状性桡动脉痉挛和桡动脉闭塞的发生率。
使用 6.5Fr 无鞘导引导管系统的手术成功率为 100%,没有需要转换为传统导引导管系统的病例。使用导管没有记录到任何与导管相关的手术并发症。在该队列中使用的辅助设备包括 IVUS、支架输送导管、远端保护装置和简单血栓切除术导管。桡动脉痉挛的发生率为 5%,2 个月时桡动脉闭塞的发生率为 2%。
使用外径<5Fr 鞘的 6.5Fr 无鞘导引导管系统作为常规 PCI 的默认系统是可行的,通过桡动脉进行的手术成功率高。