Park Jaemin, Rizzo Monica, Jackson Simona, Bates Sandra R, Green Victoria, Oprea-Ilies Gabriela
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA.
Diagn Cytopathol. 2010 Sep;38(9):663-8. doi: 10.1002/dc.21291.
Hodgkin's lymphoma is a potentially curable malignancy of the lymphatic system characterized by a variable number of scattered and large mononucleated and multinucleated tumor cells, the Hodgkin and Reed-Sternberg cells residing in an abundant heterogeneous admixture of non-neoplastic inflammatory cells. It represents approximately 30% of all lymphomas according to the World Health Organization (WHO). Patients with Hodgkin's lymphoma typically present with painless peripheral adenopathy, fever, night sweats, and weight loss. We report a rare case of Hodgkin's lymphoma presented as a breast mass in a 23-year-old woman diagnosed on fine needle aspiration (FNA). At presentation, she had no B symptoms, or palpable lymphadenopathy.
霍奇金淋巴瘤是一种潜在可治愈的淋巴系统恶性肿瘤，其特征是有数量不等的散在大单核和多核肿瘤细胞，即霍奇金和里德-斯腾伯格细胞，存在于大量非肿瘤性炎性细胞的异质性混合物中。根据世界卫生组织（WHO）的数据，它约占所有淋巴瘤的30%。霍奇金淋巴瘤患者通常表现为无痛性外周淋巴结病、发热、盗汗和体重减轻。我们报告一例罕见的霍奇金淋巴瘤，表现为一名23岁女性的乳腺肿块，通过细针穿刺抽吸活检（FNA）确诊。就诊时，她没有B症状，也没有可触及的淋巴结病。
