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[鼠疫病原体与无脊椎动物相互作用的分子机制]

[Molecular mechanisms of the plague pathogenic agent interaction with invertebrates].

作者信息

Kutyrev V V, Eroshenko G A, Popov N V, Vidiaeva N A, Konnov N P

出版信息

Mol Gen Mikrobiol Virusol. 2009(4):6-13.

PMID:20050160
Abstract

Microbe Russian Anti-Plague Research Institute, Saratov, Russia The literature data and experimental results of the authors on the molecular basis of plague agent interaction with invertebrates are discussed. The details of the plague agent life cycle, its genome organization, and molecular genetic mechanisms of its survival in flea vector and on the nematode cuticule are discussed. The experimental data about the ability to form biofilms at abiotic and biotic surfaces in the Yersinia pestis strains of the main and non-main subspecies are presented. Mechanisms of horizontal and vertical transmission of plague agent are considered. The suggestion about participation of the new member in the complex parasitic biocenosis (nematode, vector parasite) is put forward.

摘要

俄罗斯萨拉托夫微生物学俄罗斯抗鼠疫研究所 讨论了作者关于鼠疫病原体与无脊椎动物相互作用分子基础的文献数据和实验结果。讨论了鼠疫病原体生命周期的细节、其基因组组织以及在跳蚤载体和线虫角质层中生存的分子遗传机制。展示了主要和非主要亚种的鼠疫耶尔森菌菌株在非生物和生物表面形成生物膜能力的实验数据。考虑了鼠疫病原体水平和垂直传播的机制。提出了新成员参与复杂寄生生物群落(线虫、媒介寄生虫)的建议。

相似文献

1
[Molecular mechanisms of the plague pathogenic agent interaction with invertebrates].[鼠疫病原体与无脊椎动物相互作用的分子机制]
Mol Gen Mikrobiol Virusol. 2009(4):6-13.
2
Uniquely insidious: Yersinia pestis biofilms.独特的隐匿性:鼠疫耶尔森菌生物膜
Trends Microbiol. 2008 Apr;16(4):158-64. doi: 10.1016/j.tim.2008.01.005. Epub 2008 Mar 14.
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[An experimental study of the ability of the hybrid crosses of Citellophillus tesquorum fleas of 2 subspecies to transmit the causative agent of plague].[方形黄鼠蚤两个亚种杂交蚤传播鼠疫病原体能力的实验研究]
Med Parazitol (Mosk). 1995 Oct-Dec(4):14-7.
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[Flea Ceratophyllus fasciatus as the vector of the Altai-mountain strain of plague microbe].
Parazitologiia. 1977 May-Jun;11(3):268-70.
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[Enhanced blocking capacity of the plague microbe in the body of the flea].[鼠疫微生物在跳蚤体内的阻断能力增强]
Parazitologiia. 1989 Sep-Oct;23(5):427-9.
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[Phenomenon of Yersinia pestis biofilm formation in flea organism].[鼠疫耶尔森菌在跳蚤体内形成生物膜的现象]
Parazitologiia. 2009 Jul-Aug;43(4):330-7.
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[Experimental study of the infecting ability of the flea Coptopsylla lamellifer rostrata in the Kyzylkum natural focus of plague].[在克孜勒库姆鼠疫自然疫源地中,扇形栉眼蚤喙亚种感染能力的实验研究]
Parazitologiia. 2004 May-Jun;38(3):261-5.
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[Pathogenic action of the plague microbe on the flea Xenopsylla cheopis and the ultrastructure of the causative agent at various times of its stay in the vector].[鼠疫杆菌对印鼠客蚤的致病作用及其在媒介昆虫体内不同时间的病原体超微结构]
Parazitologiia. 1986 Jan-Feb;20(1):19-22.
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[Relationships of parasitic triad co-members in a Tuva natural plague focus: environmental and physiological aspects (experimental studies)].[图瓦自然鼠疫疫源地寄生三联体成员间的关系:环境与生理方面(实验研究)]
Med Parazitol (Mosk). 2004 Oct-Dec(4):36-42.
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[The effect of the vole subspecies of the plague microbe on the viability of Callopsylla caspia fleas].[鼠疫杆菌田鼠亚种对里海客蚤生存能力的影响]
Parazitologiia. 1992 Mar-Apr;26(2):105-14.

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Phylogenetic analysis of entomoparasitic nematodes, potential control agents of flea populations in natural foci of plague.鼠疫自然疫源地中跳蚤种群的潜在控制剂——昆虫寄生线虫的系统发育分析
Biomed Res Int. 2014;2014:135218. doi: 10.1155/2014/135218. Epub 2014 Apr 3.
2
The effects of modeled microgravity on growth kinetics, antibiotic susceptibility, cold growth, and the virulence potential of a Yersinia pestis ymoA-deficient mutant and its isogenic parental strain.模拟微重力对鼠疫耶尔森氏菌 ymoA 缺陷突变体及其同源亲本菌株生长动力学、抗生素敏感性、冷生长和毒力潜力的影响。
Astrobiology. 2013 Sep;13(9):821-32. doi: 10.1089/ast.2013.0968. Epub 2013 Aug 29.