Tzeis Stylianos, Luik Armin, Jilek Clemens, Schmitt Claus, Estner Heidi L, Wu Jinjin, Reents Tilko, Fichtner Stephanie, Kolb Christof, Karch Martin R, Hessling Gabriele, Deisenhofer Isabel
Deutsches Herzzentrum München & 1. Medizinische Klinik, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
J Cardiovasc Electrophysiol. 2010 Jun 1;21(6):665-70. doi: 10.1111/j.1540-8167.2009.01681.x. Epub 2009 Dec 28.
Ablation of left atrial flutter (LAF) is often limited by the need for technically demanding linear lesions. We evaluated the safety and efficacy of a new modified anterior line (MAL), connecting the anterior/anterolateral mitral annulus with the left superior pulmonary vein for ablation of perimitral flutter.
MAL was performed in 65 patients (15 females, age 63.6 +/- 9.8 years) with perimitral flutter using 3D mapping systems (70.8% Carto, 29.2% NavX). Perimitral flutter was either the presenting arrhythmia (73.8%) or an intermediate organized rhythm during atrial fibrillation ablation. Follow-up included repetitive 7-day Holter with 93.8% of patients off antiarrhythmics. MAL was acutely effective in 63/65 patients (96.9%). Termination to sinus rhythm occurred in 36 of 65 patients (55.4%), and in 27 of 65 patients (41.5%) there was a change to another LAF type. Bidirectional block across the MAL was achieved in 56 of 65 patients (86.1%). After 6 months of follow-up, 20 of 41 patients (48.8%) had a LAF recurrence, with 6 patients undergoing a reablation. In all redo patients the MAL was still complete and LAF mechanism was different to the initially targeted. No major complication occurred during the ablation procedures or in the postablation period.
The MAL is a safe and effective linear lesion for the treatment of perimitral LAF. Its value compared to more established linear lesions as the mitral isthmus line has to be evaluated in larger studies.
左房扑动(LAF)的消融常常受到技术要求高的线性消融线的限制。我们评估了一种新的改良前壁线(MAL)的安全性和有效性,该线连接二尖瓣前/前外侧环与左上肺静脉,用于消融二尖瓣周围扑动。
使用三维标测系统(70.8%为Carto,29.2%为NavX)对65例二尖瓣周围扑动患者(15例女性,年龄63.6±9.8岁)进行MAL。二尖瓣周围扑动要么是首发心律失常(73.8%),要么是房颤消融过程中的一种中间规整心律。随访包括重复进行7天动态心电图监测,93.8%的患者停用抗心律失常药物。MAL在63/65例患者(96.9%)中急性有效。65例患者中有36例(55.4%)恢复窦性心律,65例患者中有27例(41.5%)转变为另一种LAF类型。65例患者中有56例(86.1%)实现了MAL双向阻滞。随访6个月后,41例患者中有20例(48.8%)出现LAF复发,6例患者接受了再次消融。在所有再次消融的患者中,MAL仍然完整,且LAF机制与最初靶向的不同。消融过程中或消融后期间未发生重大并发症。
MAL是治疗二尖瓣周围LAF的一种安全有效的线性消融线。与更成熟的线性消融线(如二尖瓣峡部线)相比,其价值有待在更大规模的研究中评估。