Dental and Biomaterial Research, Charité Universitaetsmedizin Berlin, Assmannshauser Str 4-6, 14197 Berlin, Germany.
Acta Biomater. 2010 May;6(5):1749-55. doi: 10.1016/j.actbio.2009.12.048. Epub 2010 Jan 4.
The aim of this work was to collect and compare data from different published reports which focused on the description of the influence of different electrochemical setups for the assessment of magnesium corrosion. Based on this, a comparison with our own results, obtained for LAE 442 and AZ 31, was made and discussed. As the collection of data has shown, the reported inconsistencies between in vivo and electrochemical data depend greatly on the electrochemical medium used, on the alloy composition and on surface preparation. Nevertheless, these differences also exist when comparing different in vitro results using different methodologies and even different Mg alloys, and need therefore to be discussed more thoroughly in the future. The simulation of transport conditions of the in vivo interface should become a focus of research interest in order to gain a better understanding of the influence of connecting processes on the degradation of the biomaterials.
这项工作的目的是收集和比较不同已发表报告中的数据，这些报告主要集中描述了不同电化学设置对评估镁腐蚀的影响。在此基础上，将我们自己针对 LAE 442 和 AZ 31 获得的结果与这些报告进行了比较和讨论。正如数据收集所示，体内和电化学数据之间报告的不一致性在很大程度上取决于所使用的电化学介质、合金成分和表面准备。然而，即使在使用不同方法学甚至不同镁合金比较不同的体外结果时，也存在这些差异，因此需要在未来更深入地讨论。模拟体内界面的传输条件应该成为研究的重点，以便更好地理解连接过程对生物材料降解的影响。
