King's College London, Institute of Psychiatry, UK.
Clin Psychol Rev. 2010 Mar;30(2):269-76. doi: 10.1016/j.cpr.2009.12.001. Epub 2009 Dec 13.
A recent meta-analysis by Benish, Imel, and Wampold (2008, Clinical Psychology Review, 28, 746-758) concluded that all bona fide treatments are equally effective in posttraumatic stress disorder (PTSD). In contrast, seven other meta-analyses or systematic reviews concluded that there is good evidence that trauma-focused psychological treatments (trauma-focused cognitive behavior therapy and eye movement desensitization and reprocessing) are effective in PTSD; but that treatments that do not focus on the patients' trauma memories or their meanings are either less effective or not yet sufficiently studied. International treatment guidelines therefore recommend trauma-focused psychological treatments as first-line treatments for PTSD. We examine possible reasons for the discrepant conclusions and argue that (1) the selection procedure of the available evidence used in Benish et al.'s (2008)meta-analysis introduces bias, and (2) the analysis and conclusions fail to take into account the need to demonstrate that treatments for PTSD are more effective than natural recovery. Furthermore, significant increases in effect sizes of trauma-focused cognitive behavior therapies over the past two decades contradict the conclusion that content of treatment does not matter. To advance understanding of the optimal treatment for PTSD, we recommend further research into the active mechanisms of therapeutic change, including treatment elements commonly considered to be non-specific. We also recommend transparency in reporting exclusions in meta-analyses and suggest that bona fide treatments should be defined on empirical and theoretical grounds rather than by judgments of the investigators' intent.
贝尼什、伊梅尔和万波尔德(2008 年,《临床心理学评论》,第 28 卷,746-758)最近的一项荟萃分析得出结论,所有真正的治疗方法在创伤后应激障碍(PTSD)中同样有效。相比之下,另外七项荟萃分析或系统评价得出的结论是,有充分证据表明,以创伤为中心的心理治疗(以创伤为中心的认知行为疗法和眼动脱敏再处理)对 PTSD 有效;但不关注患者创伤记忆或其意义的治疗方法要么效果较差,要么研究不足。因此,国际治疗指南建议将以创伤为中心的心理治疗作为 PTSD 的一线治疗方法。我们检查了得出不同结论的可能原因,并认为:(1)贝尼什等人(2008 年)荟萃分析中使用的现有证据的选择程序存在偏见;(2)分析和结论没有考虑到需要证明 PTSD 的治疗方法比自然康复更有效。此外,过去二十年中以创伤为中心的认知行为疗法的效果显著增加,这与治疗内容不重要的结论相矛盾。为了进一步了解 PTSD 的最佳治疗方法,我们建议进一步研究治疗变化的积极机制,包括通常被认为是非特异性的治疗元素。我们还建议在荟萃分析中报告排除情况时保持透明,并建议根据经验和理论基础而不是根据调查人员意图的判断来定义真正的治疗方法。