Soga Yoshimitsu, Yokoi Hiroyoshi, Ando Kenji, Shirai Shinichi, Sakai Koyu, Kondo Katsuhiro, Goya Masahiko, Iwabuchi Masashi, Nobuyoshi Masakiyo
Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Eur J Cardiovasc Prev Rehabil. 2010 Apr;17(2):230-4. doi: 10.1097/HJR.0b013e3283359c4e.
Early exercise after coronary stenting is considered to have a risk of stent thrombosis (ST). We investigate the safety of submaximal exercise training based on the Borg scale from the next day after coronary stenting.
We enrolled 2351 patients who underwent successful coronary stenting. They were divided into early exercise training (EET) group (n=865) and control group (n=1486). Submaximal exercise training based on the Borg scale was performed on the next day after coronary stenting and same degree exercise was continued more than two times a week after discharge. Primary endpoint was the incidence of ST. Secondary endpoint was major adverse cardiovascular event (death, myocardial infarction, and stroke), incidence of postoperative complications, and rate of exercise continuation.
Exercise training was performed in 800 (92.5%) patients. No serious complication developed during and after exercise. Clinical follow-up data were obtained in 99% patients. At 30 days, there was no significant difference in the incidence of ST (0.58 vs. 0.47%, P=0.73), major adverse cardiovascular event (1.4 vs. 1.3%, P=0.72), and complication rate (6.9 vs. 7.3%, P=0.72). No exercise-related ST was found in either group. The rate of exercise continuation was significantly higher in the EET group (49.3 vs. 28.3%, P<0.001).
EET up to submaximal level based on the Borg scale from the day after elective coronary stenting does not increase the incidence of ST or postoperative complications.
冠状动脉支架置入术后早期运动被认为有支架血栓形成（ST）的风险。我们研究了基于自冠状动脉支架置入术后次日起的伯格量表进行的次最大运动训练的安全性。
我们纳入了2351例冠状动脉支架置入成功的患者。他们被分为早期运动训练（EET）组（n = 865）和对照组（n = 1486）。在冠状动脉支架置入术后次日进行基于伯格量表的次最大运动训练，出院后每周继续进行两次以上相同强度的运动。主要终点是ST的发生率。次要终点是主要不良心血管事件（死亡、心肌梗死和中风）、术后并发症的发生率以及运动持续率。
800例（92.5%）患者进行了运动训练。运动期间及运动后未发生严重并发症。99%的患者获得了临床随访数据。在30天时，ST的发生率（0.58%对0.47%，P = 0.73）、主要不良心血管事件（1.4%对1.3%，P = 0.72）和并发症发生率（6.9%对7.3%，P = 0.72）无显著差异。两组均未发现与运动相关的ST。EET组的运动持续率显著更高（49.3%对28.3%，P < 0.001）。
自择期冠状动脉支架置入术后次日起基于伯格量表进行的次最大水平的EET不会增加ST的发生率或术后并发症。
