Erdeve Omer, Arsan Saadet, Atasay Begum, Ileri Talia, Uysal Zumrut
Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey.
J Pediatr Hematol Oncol. 2009 Oct;31(10):763-5. doi: 10.1097/MPH.0b013e3181b7edb5.
Pregnant women with low B12 levels are unable to provide the necessary amount of this vitamin to their fetuses. The mothers are usually not anemic, and failure to thrive and neurologic deficits are more common in their infants than in megaloblastic anemia. We report the case of a newborn that was born to a vegetarian mother and presented with the symptoms of megaloblastic anemia at birth; we also discuss vitamin B12 metabolism during pregnancy and lactation. An interesting feature of the present case is that it is the only reported case of a newborn that was treated by supplementation of the mother.
维生素B12水平低的孕妇无法为胎儿提供足够量的这种维生素。母亲通常没有贫血症状，且其婴儿出现发育不良和神经功能缺损的情况比巨幼细胞贫血婴儿更为常见。我们报告了一例由素食母亲所生的新生儿，出生时即表现出巨幼细胞贫血症状；我们还讨论了孕期和哺乳期的维生素B12代谢情况。本病例的一个有趣特点是，它是唯一一例通过母亲补充维生素进行治疗的新生儿报告病例。
