Department of Neurology, Chonnam National University Medical School, Gwangju, Korea.
J Korean Med Sci. 2010 Jan;25(1):185-7. doi: 10.3346/jkms.2010.25.1.185. Epub 2009 Dec 26.
We report a 39-yr-old man with neuro-Behçet's disease (NBD) in remission who developed left-sided ataxia with a sensory deficit about 10 days after tooth extraction. Several years ago, he experienced a similar episode of relapse after tooth extraction. Brain magnetic resonance imaging showed a newly developed right thalamic lesion. In cerebrospinal fluid, lymphocyte-dominant pleocytosis and mild elevation of IgG were found. Immunologic factors may be important in the pathogenesis of NBD because of the time delay between tooth extraction and relapse. Careful observation and prevention are needed before dental procedures in patients with NBD.
我们报告了一例神经白塞病（NBD）缓解期 39 岁男性患者，在拔牙后约 10 天出现左侧共济失调伴感觉缺失。几年前，他在拔牙后也经历了类似的复发发作。脑部磁共振成像显示右侧丘脑出现新发病灶。脑脊液检查发现以淋巴细胞为主的白细胞增多和 IgG 轻度升高。由于拔牙和复发之间存在时间延迟，免疫因素在 NBD 的发病机制中可能很重要。NBD 患者在进行牙科手术前需要仔细观察和预防。
