Cooper C, Pippard E C, Sharp H, Wickham C, Chamberlain M A, Barker D J
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital.
Ann Rheum Dis. 1989 May;48(5):421-3. doi: 10.1136/ard.48.5.421.
In a comparison of 30 patients with Behçet's disease and 60 age and sex matched community controls an increased risk of Behçet's disease was associated with tonsillectomy, a history of cold sores, large sibship size, late birth order, travel to countries with high incidence of the disease, and first sexual intercourse before 16 years of age. These findings are consistent with a triggering of the disease by infection during childhood or adolescence in an immunogenetically predisposed host.
在一项对30例白塞病患者和60例年龄及性别匹配的社区对照者的比较中，白塞病风险增加与扁桃体切除术、唇疱疹病史、同胞数量多、出生顺序靠后、前往该病高发国家旅行以及16岁前首次性交有关。这些发现与在免疫遗传易感宿主的儿童期或青春期因感染引发该病相一致。
