Department of Anesthesiology, Saitama International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
J Anesth. 2010 Feb;24(1):143-5. doi: 10.1007/s00540-009-0839-z. Epub 2010 Jan 6.
We report on a patient who presented with recurrent severe shock during general anesthesia. The patient was a man scheduled for lung surgery whose first attack was a coronary spasm, which was followed by a second shock with severe bronchospasm and hypotension 4 weeks later. An elevated serum tryptase concentration was observed, and subsequent skin testing revealed negative reactions to some drugs administered in this case. This case serves to alert anesthetists to the possibility of some different forms of allergy and highlights the importance of rigorous investigation of all the reagents and phenomena.
我们报告了一例在全身麻醉期间反复出现严重休克的患者。该患者为拟行肺手术的男性，首次发作是冠状动脉痉挛，随后在 4 周后出现第二次休克，伴有严重支气管痉挛和低血压。观察到血清胰蛋白酶浓度升高，随后皮肤试验显示对该病例中使用的一些药物呈阴性反应。该病例提醒麻醉师注意可能存在一些不同形式的过敏，并强调对所有试剂和现象进行严格调查的重要性。
