Department of Health Management and Policy, College of Public Health, The University of Iowa, Iowa City, IA, USA.
Ann Surg. 2010 Feb;251(2):377-83. doi: 10.1097/SLA.0b013e3181cb853f.
There is limited published data on the relationship between hospital volume and postoperative complications. The objectives of the current study are to examine the association between hospital volume and complications and also to examine the association between complications and in-hospital mortality following 5 complex surgical procedures.
The Nationwide Inpatient Sample for years 2000 to 2003 was used. Patients who underwent coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), elective abdominal aortic aneurysm repair (AAA), pancreatectomy (PAN), and esophagectomy (ESO) as primary procedures were selected. Hospital volumes were calculated as suggested by the Leapfrog Group evidence-based hospital referral criteria. The association between hospital volume and complications were examined by multivariable logistic regression analyses, adjusting for patient and hospital characteristics.
A total of 261551 CABG, 573072 PCI, 35104 AAA, 4931 PAN, and 2473 ESO procedures were selected for analysis. A total of 580 hospitals performed the CABG procedures during the study period in this dataset. The corresponding numbers of hospitals for PCI, AAA, PAN, and ESO were 714, 1207, 758, and 555 respectively. In-hospital complication rates following CABG, PCI, AAA, PAN, and ESO were 26.45%, 6.74%, 23.81%, 39.28%, and 46.30%, respectively. High-volume hospitals for all the procedures were associated with lower odds for in-hospital mortality when compared with low-volume hospitals (P < 0.05). High-volume hospitals were associated with significantly lower odds for at least one complication following 3 of the 5 procedures (PCI, AAA, and PAN) and specifically for significantly lower odds for respiratory complications following CABG, AAA, and PAN, digestive complications following PAN, hemorrhage/hematoma complications following PCI, and septicemia following PCI and PAN when compared with low-volume hospitals (P < 0.05).
Lower mortality rates in high-volume hospitals can be partly, though not completely, attributed to lower complication rates. Future studies must focus on identifying other potential pathways for reduced mortality in high-volume hospitals.
目前关于医院手术量与术后并发症之间的关系的研究数据有限。本研究的目的是检验 5 种复杂手术中,医院手术量与并发症之间的关系,并检验并发症与住院期间死亡率之间的关系。
研究数据来源于 2000 年至 2003 年的全国住院患者样本。选取的手术包括冠状动脉旁路移植术(CABG)、经皮冠状动脉介入治疗(PCI)、择期腹主动脉瘤修复术(AAA)、胰腺切除术(PAN)和食管切除术(ESO)。根据 Leapfrog 集团基于证据的医院转诊标准,计算医院手术量。采用多变量逻辑回归分析,调整患者和医院特征,检验医院手术量与并发症之间的关系。
共纳入 261551 例 CABG、573072 例 PCI、35104 例 AAA、4931 例 PAN 和 2473 例 ESO 手术。在该数据集的研究期间,共有 580 家医院进行了 CABG 手术。PCI、AAA、PAN 和 ESO 的相应医院数量分别为 714 家、1207 家、758 家和 555 家。CABG、PCI、AAA、PAN 和 ESO 的住院并发症发生率分别为 26.45%、6.74%、23.81%、39.28%和 46.30%。与低容量医院相比,所有手术的高容量医院的住院死亡率均较低(P<0.05)。与低容量医院相比,5 种手术中的 3 种(PCI、AAA 和 PAN)和特定手术(CABG、AAA 和 PAN 术后呼吸并发症、PAN 术后消化并发症、PCI 术后出血/血肿并发症、PCI 和 PAN 术后败血症)的高容量医院发生至少一种并发症的几率显著降低(P<0.05)。
高容量医院较低的死亡率可部分归因于较低的并发症发生率。未来的研究必须集中在确定高容量医院降低死亡率的其他潜在途径上。