Allareddy Veerajalandhar, Allareddy Veerasathpurush, Konety Badrinath R
Department of Internal Medicine and Pediatrics, MetroHealth Medical Center, Cleveland, OH, USA.
Ann Surg. 2007 Jul;246(1):135-9. doi: 10.1097/01.sla.0000259823.54786.83.
Several studies have examined the association between procedure-specific volume and in-hospital mortality and concluded that high-volume hospitals have lower mortality rates when compared with low-volume hospitals. There is a paucity of studies examining the association between unrelated procedure volume and in-hospital mortality. The objective of our study is to examine the procedure-specific volume-outcome association as well as unrelated procedure volume-outcome association for 5 procedures: coronary artery bypass graft (CABG), percutaneous coronary interventions (PCI), elective abdominal aortic aneurysm repair (AAA), pancreatectomy (PAN), and esophagectomy (ESO).
Nationwide Inpatient Sample for years 2000 through 2003 was used. All discharges with primary procedure codes for CABG, PCI, AAA, PAN, and ESO were selected. The average number of procedures performed by the hospitals per year during the study period was computed, and hospitals were categorized as having met or not met the Leapfrog Group-recommended volume thresholds. Procedure specific and unrelated procedure volume-in-hospital mortality association was examined by using multivariable logistic regression analysis. Procedure volume-in-hospital mortality association was adjusted for patient and hospital characteristics.
For all 5 procedures, hospitals that did not meet Leapfrog Group volume thresholds were associated with significantly higher odds for in-hospital mortality when compared with hospitals that met Leapfrog Group volume thresholds (P < 0.05). Hospital volume levels for PAN or ESO did not influence outcomes following CABG, PCI, and AAA. Similarly, hospital volumes for CABG, PCI, and AAA did not influence the outcomes for PAN or ESO.
Hospital volume-in-hospital mortality association appears largely to be specific to the procedure being studied.
多项研究探讨了特定手术量与住院死亡率之间的关联,并得出结论:与低手术量医院相比,高手术量医院的死亡率更低。然而,关于非相关手术量与住院死亡率之间关联的研究却很少。我们研究的目的是探讨5种手术的特定手术量-结局关联以及非相关手术量-结局关联,这5种手术分别是冠状动脉搭桥术(CABG)、经皮冠状动脉介入治疗(PCI)、择期腹主动脉瘤修复术(AAA)、胰腺切除术(PAN)和食管切除术(ESO)。
使用2000年至2003年的全国住院患者样本。选取所有主要手术编码为CABG、PCI、AAA、PAN和ESO的出院病例。计算研究期间各医院每年进行的手术平均数量,并将医院分为达到或未达到“跨越组织”推荐的手术量阈值。通过多变量逻辑回归分析来研究特定手术量和非相关手术量与住院死亡率之间的关联。对手术量与住院死亡率之间的关联进行了患者和医院特征的调整。
对于所有5种手术,与达到“跨越组织”手术量阈值的医院相比,未达到该阈值的医院住院死亡率的比值显著更高(P < 0.05)。PAN或ESO的医院手术量水平并不影响CABG、PCI和AAA术后的结局。同样,CABG、PCI和AAA的医院手术量也不影响PAN或ESO的结局。
医院手术量与住院死亡率之间的关联似乎在很大程度上特定于所研究的手术。