Tristem M, Hill F, Karpas A
Department of Haematology, University of Cambridge Clinical School, U.K.
J Gen Virol. 1991 Mar;72 ( Pt 3):721-4. doi: 10.1099/0022-1317-72-3-721.
We report the complete nucleotide sequence of a human immunodeficiency virus type 2 (HIV-2) isolate from Guinea-Bissau (HIV-2CAM2). The genomic organization of HIV-2CAM2 is identical to that of other HIV-2 isolates but contains a stop codon in the pol gene. The deduced amino acid sequences of the viral proteins show variation of 20% in the gag, pol and vpx regions, and 25 to 45% in the tat, env and nef regions when compared to other isolates of HIV-2. This is greater than the variation observed between isolates of HIV-1.
