6株新的2型人类免疫缺陷病毒（HIV-2）分离株及其中1株（HIV-2CAM2）的分子特征
Six new isolates of human immunodeficiency virus type 2 (HIV-2) and the molecular characterization of one (HIV-2CAM2).
作者信息
Tristem M, Mansinho K, Champalimaud J L, Ayres L, Karpas A
机构信息
Department of Haematological Medicine, University of Cambridge Clinical School, U.K.
出版信息
J Gen Virol. 1989 Feb;70 ( Pt 2):479-84. doi: 10.1099/0022-1317-70-2-479.
PMID:2732697
Abstract
We report the isolation of human immunodeficiency virus type 2 (HIV-2) from each of six West Africans with AIDS-related complex or AIDS. One isolate (HIV-2CAM2) was molecularly cloned and shown by restriction mapping to differ in seven out of 22 sites from the prototype HIV-2ROD. Nevertheless, by a number of serological criteria these isolates are all clearly HIV-2.
摘要
我们报告了从6名患有艾滋病相关综合征或艾滋病的西非人中分离出2型人类免疫缺陷病毒（HIV-2）。对其中一个分离株（HIV-2CAM2）进行了分子克隆，并通过限制性图谱分析显示，在22个位点中有7个位点与HIV-2ROD原型不同。然而，根据一些血清学标准，这些分离株均明确为HIV-2。
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