Department of Dermatology, Kaoshiung Medical University Hospital, Kaoshiung, Taiwan.
Clin Exp Dermatol. 2009 Dec;34(8):e772-4. doi: 10.1111/j.1365-2230.2009.03498.x.
A case of untreated fusarial onychomycosis leading to serious consequences is reported. Fusarium solani is a widespread fungus and an occasional human pathogen. It usually invades rapidly in immunocompromised hosts, and often results in a poor outcome despite treatment. We report a woman with diabetes mellitus who had untreated fusarial infection of the nails, which developed into subcutaneous fusariosis, superinfected by bacteria, and then evolved into osteomyelitis that subsequently resulted in septic shock. Early management of mycotic nails in immunocompromised hosts is crucial to prevent life-threatening disease.
现报告一例未经治疗的镰刀菌甲真菌病导致严重后果的病例。茄病镰刀菌是一种广泛存在的真菌，也是一种偶发性人类病原体。它通常在免疫功能低下的宿主中迅速侵袭，并经常导致不良后果，尽管进行了治疗。我们报告了一例患有糖尿病的女性，她的指甲未经治疗就感染了镰刀菌，随后发展成皮下镰刀菌病，被细菌继发感染，然后演变成骨髓炎，最终导致感染性休克。早期治疗免疫功能低下宿主的真菌性指甲对于预防危及生命的疾病至关重要。
