Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India,
Mycopathologia. 2013 Oct;176(3-4):225-32. doi: 10.1007/s11046-013-9646-z. Epub 2013 Jun 30.
Fungal infections of foot in patients with diabetes are not uncommon; however, foot infection due to Fusarium species has been rarely reported. We report here a case of a 50-year-old male with type 2 diabetes who developed multiple spontaneous nodular lesions on right foot without any systemic symptoms and signs for 6 months. The lesions were unresponsive to broad-spectrum antibacterial treatment. Fine needle aspiration cytology of nodular lesions revealed the presence of fungal hyphae, and Fusarium species was isolated from the same sample which was identified as Fusarium solani species complex: Fusarium falciforme. Radiological investigations and blood culture ruled out any dissemination of the disease. The lesions healed after voriconazole therapy for 3 months. No relapse was noted at the end of the next 6-month follow-up. All reported cases of Fusarium infection of foot in patients with diabetes in English and non-English literature since 1970 have been reviewed.
糖尿病患者足部真菌感染并不少见；然而，由镰刀菌属引起的足部感染却很少见。我们在此报告一例 50 岁男性，患有 2 型糖尿病，6 个月来无任何全身症状和体征的情况下，右脚出现多个自发性结节性病变。病变对广谱抗菌治疗无反应。结节病变的细针抽吸细胞学检查显示存在真菌菌丝，从同一样本中分离出镰刀菌属，鉴定为镰孢属 solani 种复合体：镰孢 falciforme。放射学检查和血培养排除了任何疾病的播散。经伏立康唑治疗 3 个月后，病变愈合。在接下来的 6 个月随访结束时，没有发现复发。自 1970 年以来，所有以英文和非英文文献形式报告的糖尿病患者足部镰刀菌感染病例均进行了回顾。
