Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Artillerigatan 12, Linköping, Sweden.
Forensic Sci Int. 2010 May 20;198(1-3):17-22. doi: 10.1016/j.forsciint.2009.12.015. Epub 2010 Jan 6.
Specimens of blood and other body fluids were obtained at autopsy from all deaths in Sweden classified as suicide covering a 10-year period (N=11,441 cases). The mean age (+/-standard deviation, SD) of the victims was 51.3+/-18.8 years with a clear predominance of males 71% (mean age 51.3+/-18.8 years) compared with 29% females (mean age 51.4+/-18.9 years). The concentration of ethanol in blood samples was determined in duplicate by headspace gas chromatography and a mean blood-alcohol concentration (BAC) of 0.1g/L (10mg/100mL) was the cut-off used to identify ethanol positive cases. The suicides were coded (ICD-9) as self-poisonings (N=2462, 22%), hanging (N=4474, 39%), asphyxia by gas (N=509, 4.4%), drowning (N=803, 7.0%), gun shot (N=1307, 11.4%), fall from height (N=632, 5.5%), self-inflicted cuts or sharp-force injury (N=363, 3.1%) and miscellaneous ways (N=891, 7.8%). On average 34% of all suicide victims in Sweden had consumed alcohol before death, 36% of the males and 31% of the females had a positive BAC. The mean (median) concentration of alcohol in femoral blood for men was 1.34g/L (1.3g/L) compared with 1.25g/L (1.1g/L) for women. Many victims were heavily intoxicated and the 90th percentiles of the BAC distributions ranged from 2.3 to 2.8g/L depending on manner of death. Elevated blood-alcohol was most prevalent in poisoning deaths (45%) and gas asphyxia (51%) and least prevalent in falls from height (19%) and sharp-force injury (18%). Toxicological analysis for presence of drugs other than alcohol showed a predominance of paracetamol, SSRI antidepressants, anti-psychotics, sedative-hypnotics, and centrally acting opioids. A host of psycho-social factors drive a person to commit suicide and one of the catalysts is over-consumption of alcohol and acute alcohol intoxication. Heavy drinking leads to a loss of inhibitions, impulsive behaviour, poor judgment and a tendency to take risks, all of which might increase the propensity of predisposed individuals to take their own lives.
在瑞典,对所有被归类为自杀的死亡案例进行了 10 年的尸检,共获得了 11441 例血液和其他体液样本。受害者的平均年龄(+/-标准差,SD)为 51.3+/-18.8 岁,男性明显占多数,占 71%(平均年龄 51.3+/-18.8 岁),而女性占 29%(平均年龄 51.4+/-18.9 岁)。通过顶空气相色谱法对血液样本中的乙醇浓度进行了双重测定,0.1g/L(10mg/100mL)的平均血液酒精浓度(BAC)被用作确定乙醇阳性病例的截断值。自杀行为被 ICD-9 编码为自毒(N=2462,22%)、上吊(N=4474,39%)、气体窒息(N=509,4.4%)、溺水(N=803,7.0%)、枪击(N=1307,11.4%)、从高处坠落(N=632,5.5%)、自残或锐器伤(N=363,3.1%)和其他方式(N=891,7.8%)。瑞典平均有 34%的自杀受害者在死亡前饮酒,其中 36%的男性和 31%的女性 BAC 呈阳性。男性股动脉血液中酒精的平均(中位数)浓度为 1.34g/L(1.3g/L),而女性为 1.25g/L(1.1g/L)。许多受害者处于高度醉酒状态,BAC 分布的第 90 百分位数因死亡方式而异,范围从 2.3 到 2.8g/L。血液酒精升高在中毒死亡(45%)和气体窒息(51%)中最为常见,在从高处坠落(19%)和锐器伤(18%)中最为罕见。除酒精以外的其他药物的毒理学分析显示,扑热息痛、SSRIs 抗抑郁药、抗精神病药、镇静催眠药和中枢作用阿片类药物占主导地位。一系列心理社会因素促使一个人自杀,其中一个催化剂是过度饮酒和急性酒精中毒。大量饮酒会导致抑制作用丧失、冲动行为、判断力差和冒险倾向增加,所有这些都可能增加有自杀倾向的人的自杀倾向。