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瑞典自杀者的人口统计学特征与其血液酒精浓度以及死亡的情况和方式有关。

Demographics of suicide victims in Sweden in relation to their blood-alcohol concentration and the circumstances and manner of death.

机构信息

Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Artillerigatan 12, Linköping, Sweden.

出版信息

Forensic Sci Int. 2010 May 20;198(1-3):17-22. doi: 10.1016/j.forsciint.2009.12.015. Epub 2010 Jan 6.

Abstract

Specimens of blood and other body fluids were obtained at autopsy from all deaths in Sweden classified as suicide covering a 10-year period (N=11,441 cases). The mean age (+/-standard deviation, SD) of the victims was 51.3+/-18.8 years with a clear predominance of males 71% (mean age 51.3+/-18.8 years) compared with 29% females (mean age 51.4+/-18.9 years). The concentration of ethanol in blood samples was determined in duplicate by headspace gas chromatography and a mean blood-alcohol concentration (BAC) of 0.1g/L (10mg/100mL) was the cut-off used to identify ethanol positive cases. The suicides were coded (ICD-9) as self-poisonings (N=2462, 22%), hanging (N=4474, 39%), asphyxia by gas (N=509, 4.4%), drowning (N=803, 7.0%), gun shot (N=1307, 11.4%), fall from height (N=632, 5.5%), self-inflicted cuts or sharp-force injury (N=363, 3.1%) and miscellaneous ways (N=891, 7.8%). On average 34% of all suicide victims in Sweden had consumed alcohol before death, 36% of the males and 31% of the females had a positive BAC. The mean (median) concentration of alcohol in femoral blood for men was 1.34g/L (1.3g/L) compared with 1.25g/L (1.1g/L) for women. Many victims were heavily intoxicated and the 90th percentiles of the BAC distributions ranged from 2.3 to 2.8g/L depending on manner of death. Elevated blood-alcohol was most prevalent in poisoning deaths (45%) and gas asphyxia (51%) and least prevalent in falls from height (19%) and sharp-force injury (18%). Toxicological analysis for presence of drugs other than alcohol showed a predominance of paracetamol, SSRI antidepressants, anti-psychotics, sedative-hypnotics, and centrally acting opioids. A host of psycho-social factors drive a person to commit suicide and one of the catalysts is over-consumption of alcohol and acute alcohol intoxication. Heavy drinking leads to a loss of inhibitions, impulsive behaviour, poor judgment and a tendency to take risks, all of which might increase the propensity of predisposed individuals to take their own lives.

摘要

在瑞典,对所有被归类为自杀的死亡案例进行了 10 年的尸检,共获得了 11441 例血液和其他体液样本。受害者的平均年龄(+/-标准差,SD)为 51.3+/-18.8 岁,男性明显占多数,占 71%(平均年龄 51.3+/-18.8 岁),而女性占 29%(平均年龄 51.4+/-18.9 岁)。通过顶空气相色谱法对血液样本中的乙醇浓度进行了双重测定,0.1g/L(10mg/100mL)的平均血液酒精浓度(BAC)被用作确定乙醇阳性病例的截断值。自杀行为被 ICD-9 编码为自毒(N=2462,22%)、上吊(N=4474,39%)、气体窒息(N=509,4.4%)、溺水(N=803,7.0%)、枪击(N=1307,11.4%)、从高处坠落(N=632,5.5%)、自残或锐器伤(N=363,3.1%)和其他方式(N=891,7.8%)。瑞典平均有 34%的自杀受害者在死亡前饮酒,其中 36%的男性和 31%的女性 BAC 呈阳性。男性股动脉血液中酒精的平均(中位数)浓度为 1.34g/L(1.3g/L),而女性为 1.25g/L(1.1g/L)。许多受害者处于高度醉酒状态,BAC 分布的第 90 百分位数因死亡方式而异,范围从 2.3 到 2.8g/L。血液酒精升高在中毒死亡(45%)和气体窒息(51%)中最为常见,在从高处坠落(19%)和锐器伤(18%)中最为罕见。除酒精以外的其他药物的毒理学分析显示,扑热息痛、SSRIs 抗抑郁药、抗精神病药、镇静催眠药和中枢作用阿片类药物占主导地位。一系列心理社会因素促使一个人自杀,其中一个催化剂是过度饮酒和急性酒精中毒。大量饮酒会导致抑制作用丧失、冲动行为、判断力差和冒险倾向增加,所有这些都可能增加有自杀倾向的人的自杀倾向。

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