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全球感知效应量表为评估肌肉骨骼疾病患者的健康转归提供了可靠的评估,但评分受到当前状况的强烈影响。

Global Perceived Effect scales provided reliable assessments of health transition in people with musculoskeletal disorders, but ratings are strongly influenced by current status.

机构信息

The George institute, University of Sydney, PO Box M201 Missenden Rd, Camperdown, NSW 2050, Australia.

出版信息

J Clin Epidemiol. 2010 Jul;63(7):760-766.e1. doi: 10.1016/j.jclinepi.2009.09.009. Epub 2010 Jan 8.

Abstract

OBJECTIVE

The study investigated the test-retest reliability and construct validity of the Global Perceived Effect (GPE) scale in patients with musculoskeletal disorders.

STUDY DESIGN AND SETTING

Data from seven clinical studies including 861 subjects were used for the analyses. Repeat measures taken at the same attendance and from attendances separated by 24 hours were compared to estimate test-retest reliability. Construct validity was evaluated by examining relationships between pre, post, and change scores in pain and disability measures with GPE measures.

RESULTS

Intraclass correlation coefficient values of 0.90-0.99 indicate excellent reproducibility of the GPE scale. In all but one data set, change scores on pain and disability measures correlated well (r=0.40-0.74) with GPE; however, post scores nearly always correlated even more strongly (r=0.58-0.84), and pre scores showed much weaker association (r=0.00-0.28). Pre scores accounted for only a small amount of additional R(2) when added to regression models including post score.

CONCLUSIONS

Test-retest reliability of the GPE is excellent. GPE ratings are strongly influenced by current status, with the effect more obvious as transition time lengthens. This result questions whether transition ratings truly reflect change, or rather just current state. This finding also has implications for the use of GPE ratings as an external criterion of change in clinimetric studies.

摘要

目的

本研究旨在调查肌肉骨骼疾病患者全球感知疗效(GPE)量表的重测信度和结构效度。

研究设计和设置

对 7 项临床研究的数据(共 861 名受试者)进行分析。通过比较同一就诊时和相隔 24 小时就诊时的重复测量值,评估重测信度。通过考察疼痛和残疾测量的前后和变化分数与 GPE 测量之间的关系,评估结构效度。

结果

0.90-0.99 的组内相关系数值表明 GPE 量表具有极好的可重复性。在除一个数据集之外的所有数据集中,疼痛和残疾测量的变化分数与 GPE 相关性良好(r=0.40-0.74);然而,后测分数几乎总是相关性更强(r=0.58-0.84),前测分数相关性较弱(r=0.00-0.28)。当在后测分数包含的回归模型中加入前测分数时,其仅能额外解释较小的 R²(0.00-0.28)。

结论

GPE 的重测信度极好。GPE 评分受当前状态影响较大,随着过渡期延长,其影响更为明显。这一结果对 GPE 评分作为临床疗效研究中变化的外部标准提出了质疑,其是否真正反映了变化,还是仅仅反映了当前状态。这一发现也对 GPE 评分在临床疗效研究中作为变化的外部标准的使用具有重要意义。

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