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癫痫/发作患者受伤死亡地点的差异。

Disparities in injury death location for people with epilepsy/seizures.

机构信息

Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

出版信息

Epilepsy Behav. 2010 Mar;17(3):369-72. doi: 10.1016/j.yebeh.2009.12.011. Epub 2010 Jan 6.

Abstract

OBJECTIVE

Wide variation has been reported in the proportion of injury deaths occurring during the prehospital phase. Potential disparities in where injured people with epilepsy and seizure disorders die have not been examined. We compared location of death between injured patients with epilepsy and seizure disorders and similar patients without epilepsy/seizures and tested the hypothesis that injured people with epilepsy/seizures are more likely to die outside of a hospital or health care setting.

METHODS

U.S. vital statistics (mortality) data from the multiple cause of death files of the National Center for Health Statistics were analyzed. Patients less than 65 years of age at death who had injury as the underlying cause of death were included. Multinomial logistic regression was used to assess location of death, controlling for patient and injury characteristics.

RESULTS

Controlling for potential confounders, people with epilepsy/seizures were more likely to die at home from unintentional injuries (relative risk ratio [RRR]=1.51, P<0.001) and less likely to die in public places (RRR=0.27, P<0.001). People with epilepsy/seizures were less likely to die at home or in public places from suicide, but significantly more likely to die at home from homicide (RRR=2.29, P<0.001). By mechanism of injury, people with epilepsy/seizures were more likely to die at home from drowning (RRR=2.35, P<0.001).

DISCUSSION

Disparities in where injured people with epilepsy/seizures die deserve further attention. Identifying the underlying causes of these disparities will allow for the development of targeted prevention interventions.

摘要

目的

据报道,伤患在院前阶段死亡的比例存在很大差异。尚未研究过患有癫痫和癫痫发作障碍的伤患与其他伤患在何处死亡存在潜在差异。我们比较了患有癫痫和癫痫发作障碍的伤患与无癫痫/癫痫发作的类似伤患的死亡地点,并检验了这样一个假设,即患有癫痫/癫痫发作的伤患更有可能在医院或医疗保健场所之外死亡。

方法

我们分析了美国国家卫生统计中心多病因死亡档案中的美国人口动态统计(死亡率)数据。将死亡时年龄小于 65 岁且损伤为根本死因的患者纳入研究。采用多项逻辑回归分析评估死亡地点,同时控制患者和损伤特征。

结果

在控制潜在混杂因素后,癫痫/癫痫发作患者因非故意损伤而更有可能在家中死亡(相对风险比 [RRR]=1.51,P<0.001),而不太可能在公共场所死亡(RRR=0.27,P<0.001)。癫痫/癫痫发作患者因自杀而更有可能在家中或公共场所死亡的可能性较小,但因他杀而在家中死亡的可能性显著更大(RRR=2.29,P<0.001)。按损伤机制分类,癫痫/癫痫发作患者因溺水而更有可能在家中死亡(RRR=2.35,P<0.001)。

讨论

伤患因癫痫/癫痫发作而死亡的地点存在差异,值得进一步关注。确定这些差异的根本原因将有助于制定有针对性的预防干预措施。

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