Unidad de Arritmias, Servicio de Cardiología, Hospital Universitario Doce de Octubre, Madrid, Spain.
Europace. 2010 Mar;12(3):364-70. doi: 10.1093/europace/eup421. Epub 2010 Jan 6.
To assess the performance of AF-QoL, a quality of life questionnaire for patients with atrial fibrillation (AF).
Observational, prospective, multicentre study in 29 Spanish centres. Three patients' groups were identified at baseline visit: AF patients receiving a new therapeutic intervention according to physician criteria (intervention group); AF clinically stable patients according to physician evaluation (clinically stable group); and patients in a stable condition for more than 1 year after a myocardial infarction (control group). All patients were > or = 18 years. Follow-up visit was at 1 month (clinically stable group) and 3 +/- 1 months (intervention group). Sociodemographic and clinical information was gathered. AF-QoL, SF-36, and patient self-perception of general health status were administered. A total of 417 patients was included. Mean (SD) age was 61.2 (12.4), 31.4% women. AF-QoL mean overall score in AF patients (43.6) was lower (worse health-related quality of life, HRQoL) than in the control group (51.7) (P < 0.05). At baseline, patients with higher frequency of symptoms (P < 0.05) and worse NYHA functional class (P < 0.01) reported lower AF-QoL scores. AF-QoL and SF-36 correlated in all of their domains (r = 0.14-0.8, P < 0.01). AF-QoL showed good internal consistency (0.92) and test-retest reliability (0.86).
AF-QoL is a valid and reliable HRQoL measure. Further investigation is recommended before using it in clinical practice.
评估 AF-QoL，一种用于心房颤动（AF）患者的生活质量问卷的性能。
在 29 个西班牙中心进行的观察性、前瞻性、多中心研究。在基线就诊时确定了三组患者：根据医生标准接受新治疗干预的 AF 患者（干预组）；根据医生评估 AF 临床稳定的患者（临床稳定组）；以及心肌梗死后 1 年以上稳定状况的患者（对照组）。所有患者年龄均> = 18 岁。随访就诊时间为 1 个月（临床稳定组）和 3 +/- 1 个月（干预组）。收集社会人口统计学和临床信息。进行 AF-QoL、SF-36 和患者对一般健康状况的自我感知评估。共纳入 417 例患者。平均（标准差）年龄为 61.2（12.4），31.4%为女性。AF 患者的 AF-QoL 总体平均得分（43.6）低于对照组（51.7）（P < 0.05）。在基线时，症状频率较高的患者（P < 0.05）和 NYHA 功能分级较差的患者（P < 0.01）报告的 AF-QoL 评分较低。AF-QoL 与 SF-36 在其所有领域均相关（r = 0.14-0.8，P < 0.01）。AF-QoL 具有良好的内部一致性（0.92）和重测信度（0.86）。
AF-QoL 是一种有效的、可靠的 HRQoL 测量工具。建议在临床实践中使用之前进行进一步的研究。
