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加利福尼亚州圣华金谷的室外空气污染与未控制的哮喘。

Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California.

机构信息

UCLA Center for Health Policy Research, Los Angeles, California, USA.

出版信息

J Epidemiol Community Health. 2010 Feb;64(2):142-7. doi: 10.1136/jech.2009.083576.

Abstract

BACKGROUND

The San Joaquin Valley (SJV) in California ranks among the worst in the USA in terms of air quality, and its residents report some of the highest rates of asthma symptoms and asthma-related emergency department (ED) visits and hospitalisations in California. Using California Health Interview Survey data, the authors examined associations between air pollution and asthma morbidity in this region.

METHODS

Eligible subjects were SJV residents (2001 California Health Interview Survey) who reported physician-diagnosed asthma (n=1502, 14.6%). The authors considered two outcomes indicative of uncontrolled asthma: (1) daily or weekly asthma symptoms and (2) asthma-related ED visits or hospitalisation in the past year. Based on residential zip code, subjects were assigned annual average concentrations of ozone, PM(10) and PM(2.5) for the 1-year period prior to the interview date from their closest government air monitoring station within an 8 km (5 miles) radius.

RESULTS

Adjusting for age, gender, race/ethnicity, poverty level and insurance status, the authors observed increased odds of experiencing daily or weekly asthma symptoms for ozone, PM(10) and PM(2.5) (OR(ozone) 1.23, 95% CI 0.94 to 1.60 per 10 ppb; OR(PM10) 1.29, 95% CI 1.05 to 1.57 per 10 microg/m(3); and OR(PM2.5) 1.82; 95% CI 1.11 to 2.98 per 10 microg/m(3)). The authors also observed increased odds of asthma-related ED visits or hospitalisations for ozone (OR 1.49, 95% CI 1.05 to 2.11 per 10 ppb) and a 29% increase in odds for PM(10) (OR 1.29, 95% CI 0.99 to 1.69 per 10 microg/m(3)).

CONCLUSIONS

Overall, these findings suggest that individuals with asthma living in areas of the SJV with high ozone and particulate pollution levels are more likely to have frequent asthma symptoms and asthma-related ED visits and hospitalisations.

摘要

背景

加利福尼亚州的圣华金谷(SJV)在空气质量方面在美国排名最差,其居民报告的哮喘症状和与哮喘相关的急诊室(ED)就诊和住院率在加利福尼亚州也是最高的。本文作者利用加利福尼亚州健康访谈调查数据,研究了该地区空气污染与哮喘发病率之间的关系。

方法

符合条件的研究对象为报告有医生诊断的哮喘的 SJV 居民(2001 年加利福尼亚州健康访谈调查)(n=1502,占 14.6%)。作者考虑了两个表明哮喘未得到控制的结果:(1)每日或每周的哮喘症状,(2)过去一年中与哮喘相关的 ED 就诊或住院。根据居住的邮政编码,以受访者居住地址为中心,以 8 公里(5 英里)为半径,在其最近的政府空气监测站获得受访者在接受访谈前 1 年的臭氧、PM(10)和 PM(2.5)的年平均浓度。

结果

在调整年龄、性别、种族/民族、贫困水平和保险状况后,作者观察到臭氧、PM(10)和 PM(2.5)浓度每增加 10 微克/立方米,每日或每周哮喘症状的发生风险增加(臭氧 OR1.23,95%CI 0.94 至 1.60;PM(10)OR1.29,95%CI 1.05 至 1.57;PM(2.5)OR1.82,95%CI 1.11 至 2.98)。作者还观察到臭氧浓度每增加 10 微克/立方米,与哮喘相关的 ED 就诊或住院的风险增加 1.49 倍(95%CI 1.05 至 2.11),PM(10)浓度每增加 10 微克/立方米,风险增加 29%(OR1.29,95%CI 0.99 至 1.69)。

结论

总的来说,这些发现表明,生活在 SJV 臭氧和颗粒物污染水平较高地区的哮喘患者,更有可能出现频繁的哮喘症状和与哮喘相关的 ED 就诊和住院。

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