Mastoraki Aikaterini, Papanikolaou Ioannis S, Kanakis Dimitrios, Safioleas Panagiotis, Sakorafas George, Safioleas Michael
4th Department of Surgery, Medical School, ATTIKON University Hospital, Athens University, 1 Rimini str., 12462, Chaidari, Athens, Greece.
J Gastrointest Cancer. 2010 Jun;41(2):141-4. doi: 10.1007/s12029-009-9123-6.
Signet ring carcinoma (SRC) of the appendix consists one of the most biologically virulent cancers. We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix.
A 78-year-old man was admitted due to a 5-day history of increasing colicky abdominal pain and vomiting. Clinical examination revealed a firm, tender mass in the right ileac fossa. Laparotomy confirmed a tumor mass which appeared to originate from the appendix. The affected part of the bowel was resected and a right hemicolectomy with an end-to-side ileotransverse anastomosis was performed. The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. Moreover, a focus of SRC was detected.
Appendiceal SRC is a rare entity, which may sometimes be confused with other pathologies providing difficulties in differential diagnosis, having an impact on therapeutic decisions and affecting prognosis.
阑尾印戒细胞癌（SRC）是生物学上最具侵袭性的癌症之一。我们报告一例原发性阑尾SRC并发阑尾急性炎症的病例。
一名78岁男性因5天来阵发性腹痛加剧和呕吐入院。临床检查发现右髂窝有一个质地硬、有压痛的肿块。剖腹手术证实有一个似乎起源于阑尾的肿瘤肿块。切除受累肠段并进行了右半结肠切除术及端侧回肠横结肠吻合术。阑尾明显增厚，壁有溃疡，伴有窦道、慢性炎症和瘢痕形成。此外，还检测到一个SRC病灶。
阑尾SRC是一种罕见的疾病，有时可能与其他病理情况混淆，给鉴别诊断带来困难，影响治疗决策和预后。
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