Nakanishi Masaki, Kubota Yutaka, Hara Hiroshi, Ueda Mikio, Arimoto Taichiro, Iwasaki Yoshinobu
Department of Pulmonary Medicine, Kyoto Second Red Cross Hospital.
Nihon Kokyuki Gakkai Zasshi. 2009 Dec;47(12):1135-40.
A 69 year-old man was admitted to our hospital with bloody sputum and abnormal shadows in his chest X-ray film and CT. According to the bronchoscopic examination, he was diagnosed as suffering from small cell lung cancer (SCLC). Aside from SCLC, erythroderma, lymphoadenopathy and abnormal lymphoid cells in his peripheral blood were recognized on admission. Considering possible disorder blood complications, we conducted examinations including a biopsy of the skin and superficial lymph nodes, which revealed the characteristics of Sézary syndrome. We provided local treatment for Sézary syndrome and did systemic chemotherapy with carboplatin and etoposide for SCLC. After four cycles of chemotherapy, the patient showed a partial response. We report a very rare case of SCLC with Sézary syndrome in which we were able to provide chemotherapy effectively and safely.
一名69岁男性因咯血痰以及胸部X光片和CT显示异常阴影入住我院。根据支气管镜检查，他被诊断为患有小细胞肺癌（SCLC）。入院时，除了SCLC外，还发现有红皮病、淋巴结病以及外周血中异常淋巴细胞。考虑到可能存在血液系统并发症，我们进行了包括皮肤和浅表淋巴结活检在内的检查，结果显示为塞扎里综合征的特征。我们对塞扎里综合征进行了局部治疗，并对SCLC采用卡铂和依托泊苷进行全身化疗。经过四个周期的化疗，患者显示出部分缓解。我们报告了一例非常罕见的SCLC合并塞扎里综合征病例，在此病例中我们能够有效且安全地进行化疗。
