Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA.
Am J Obstet Gynecol. 2010 Apr;202(4):348.e1-7. doi: 10.1016/j.ajog.2009.11.032. Epub 2010 Jan 8.
The purpose of this study was to describe health-related quality of life and satisfaction after global endometrial ablation in women with bleeding disorders and a systematic review of the literature.
A follow-up survey was mailed to 36 patients with bleeding disorders and 110 reference patients (no coagulopathies) who underwent global endometrial ablation for menorrhagia. The survey included a generic (SF-12) and menorrhagia multi-attribute utility scale questionnaires.
Ninety-six women (66%) responded. The total menorrhagia multiattribute utility scale score increased from 35-100 in bleeding disorder cohort (P = .03) and from 48-100 in the reference cohort (P < .001). Although postablation SF-12 mental domain scores were comparable in both cohorts (55 vs 55; P = .67), physical domain scores were lower in the bleeding disorder cohort (50 vs 56; P < .001). High satisfaction was reported by both cohorts (95% vs 84%; P = .60).
Global endometrial ablation improved health-related quality of life for women with bleeding disorders and had high satisfaction rates.
本研究旨在描述出血性疾病患者行全球子宫内膜消融术后的健康相关生活质量和满意度，并对相关文献进行系统回顾。
对 36 例出血性疾病患者和 110 例参照患者（无凝血功能障碍）进行了随访调查，这些患者均因月经过多而行全球子宫内膜消融术。调查包括一般健康状况（SF-12）和月经过多多属性效用量表问卷。
96 名女性（66%）做出了回应。出血性疾病组的总月经过多多属性效用量表评分从 35-100 分增加（P =.03），参照组从 48-100 分增加（P <.001）。尽管消融术后 SF-12 心理领域评分在两组中相当（55 分比 55 分；P =.67），但出血性疾病组的生理领域评分较低（50 分比 56 分；P <.001）。两组均报告了较高的满意度（95%比 84%；P =.60）。
全球子宫内膜消融术改善了出血性疾病患者的健康相关生活质量，且满意度较高。
