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自体颅骨骨移植与异体材料用于颅骨缺损二期重建的比较评估

Comparative evaluation of autogenous calvarial bone graft and alloplastic materials for secondary reconstruction of cranial defects.

作者信息

Sahoo Nandakishor, Roy Indranil Deb, Desai Ajay Premanand, Gupta Vishal

机构信息

Department Oral and Maxillofacial Surgery, Army Dental Centre, Army Hospital (R&R), Delhi Cantt-10, India.

出版信息

J Craniofac Surg. 2010 Jan;21(1):79-82. doi: 10.1097/SCS.0b013e3181c3ba58.

Abstract

OBJECTIVE

To do a comparative study and evaluate the outcome in healing of reconstructed cranial defects with an autogenous bone graft vis-à-vis alloplastic materials.

METHODS

A total of 22 patients with cranial defects were selected for this study. All the subjects were men; mean age was 27 years. Secondary reconstruction was done to obturate the defects. Of the 22 patients, 11 underwent cranioplasty with autogenous calvarial bone graft, 6 patients with a titanium mesh and 5 with a polymethylmethacrylate plate.

RESULTS

The follow-up period ranged from 18 to 24 months. The 11 patients who were operated on with autogenous calvarial bone grafts did not develop any postoperative infection or complications. Graft uptake was complete, and the contour of the skull was improved in all the patients. Of the 5 patients operated on for secondary reconstruction with polymethylmethacrylate plates, 3 had exposure of the implant and 1 reported with secondary infection. Of the patients where secondary reconstruction was carried out with a titanium mesh only, 1 reported with secondary infection and 2 reported with thermal sensitivity. No graft resorption was detected.

CONCLUSIONS

In our study, we concluded that autogenous calvarial bone grafts have better mechanical, biologic, and immunologic properties. This procedure allows the surgeon to reconstruct moderately large cranial defect with ease of access within single or adjacent incision to the operating site with minimal postoperative morbidity and discomfort.

摘要

目的

进行一项对比研究,评估自体骨移植与异体材料修复颅骨缺损的愈合效果。

方法

本研究共选取22例颅骨缺损患者。所有受试者均为男性,平均年龄27岁。进行二期修复以封闭缺损。22例患者中,11例行自体颅骨骨移植颅骨成形术,6例采用钛网,5例采用聚甲基丙烯酸甲酯板。

结果

随访期为18至24个月。11例行自体颅骨骨移植手术的患者未发生任何术后感染或并发症。移植骨完全吸收,所有患者的颅骨外形均得到改善。5例行聚甲基丙烯酸甲酯板二期修复手术的患者中,3例植入物外露,1例出现继发感染。仅采用钛网进行二期修复的患者中,1例出现继发感染,2例出现热敏感。未检测到移植骨吸收。

结论

在我们的研究中,我们得出结论,自体颅骨骨移植具有更好的机械、生物学和免疫学特性。该手术使外科医生能够在单个或相邻手术切口内轻松接近手术部位,以最小的术后发病率和不适感修复中度大的颅骨缺损。

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